A wooden bench in a forest with a natural backdrop of trees and foliage.

Spa Hotels & Resorts in Southeastern Indiana from NZ$154

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeastern Indiana Spa Hotels

Tonight
21 Oct - 22 Oct
Tomorrow
22 Oct - 23 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Southeastern Indiana hotels with a spa

A restaurant with round tables, chairs, chandeliers, and a bar area.
A spacious lobby with a geometric chandelier, a reception desk, and a red accent wall.
A large hotel with a prominent 'Caesars' sign, multiple floors, and a symmetrical facade.
A casino with multiple gaming tables and slot machines, a red carpet, and ornate chandeliers.

1. Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination

Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
Elizabeth
  • Refresh your spirit at this riverfront hotel with daily spa treatments and couples rooms, where aromatherapy and Ayurvedic therapies await.
NZ$154
includes taxes & fees
19 Nov - 20 Nov
Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A modern bathroom with a shower, a sink, and a large mirror.
A steam fountain in a brick alleyway.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

2. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
  • Experience a rejuvenating spa escape at this luxury boutique hotel with massage rooms and 24-hour fitness centre in city centre Louisville.
NZ$342
includes taxes & fees
15 Nov - 16 Nov
21c Museum Hotel Louisville
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A balcony with a view of a river, a bridge, and a cityscape.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.
An outdoor patio with black tables and chairs, surrounded by large windows and a row of arches.

3. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
  • Riverside sanctuary offers rejuvenating spa treatments, panoramic fitness views, and river-facing balconies for a relaxing urban retreat.
NZ$291
includes taxes & fees
8 Nov - 9 Nov
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.
A modern interior with a fireplace, bookshelves, and seating areas.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.

4. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
  • Immerse in spa bliss at this Louisville hotel where Mokara Spa offers therapeutic treatments and rooftop relaxation awaits.
NZ$421
includes taxes & fees
16 Nov - 17 Nov
Omni Louisville Hotel
A treatment room with a massage table, a desk with a computer, and a large mirror.
A luxurious bathroom with a large mirror, a bathtub, and a shower area.
A golf course with a flag, a sand bunker, and a building in the background.
A large, multi-story hotel with a prominent dome and arched windows, featuring a well-lit entrance and landscaped gardens.

5. Belterra Casino Resort

Belterra Casino Resort
Florence
  • Experience soothing river views and rejuvenating spa treatments at this hotel with indoor and outdoor pools.
NZ$272
includes taxes & fees
4 Nov - 5 Nov
Belterra Casino Resort
A hotel lobby with a chandelier, wooden railings, a reception desk, and a large arched doorway.
A conference room with multiple tables and chairs, a flat-screen TV mounted on the wall, and a large window with blinds.
A hotel room with a bed, desk, chair, and a green accent wall.
An indoor swimming pool with clear water, surrounded by lounge chairs and a small seating area.

6. Quality Inn Seymour I-65

Quality Inn Seymour I-65
Seymour
  • Revitalise your body and spirit in this tranquil hotel featuring a full-service daily spa, indoor pool, and 24-hour fitness centre.
NZ$159
includes taxes & fees
19 Nov - 20 Nov
Quality Inn Seymour I-65
A rustic bar area with a wooden bar counter, stools, and a variety of bottles and glasses.
A living room with a sofa, coffee table, and a television mounted on the wall.
A cozy room with a wooden wall, a sofa, and a dining table.
A porch with white rocking chairs and a table, a window with blinds, and a view of a green landscape.

7. Pillow and Paddock B&B

Pillow and Paddock B&B
La Grange
  • Relax in a cosy bed and breakfast retreat with a steamy spa pool, rejuvenating spa services, and a peaceful garden sanctuary.
NZ$647
includes taxes & fees
10 Nov - 11 Nov
Pillow and Paddock B&B
View all properties

Choose what matters most at spa hotels in Southeastern Indiana

Pool
Breakfast included
Spa pool
4 stars
5 stars

Top Southeastern Indiana Hotel Reviews

Hyatt Select Louisville North

Hyatt Select Louisville North

8/10 Good
"Liked - breakfast (very good), workout equipment (nice treadmill), room access (1st floor) Disliked - no pool, no guide to TV channels, hotel was a bit hard to find, outside lighting shines in window"
Glen 2-night trip
Posted 5 hours ago
Hyatt Select Louisville North
Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

10/10 Excellent
"remodeled recently. very clean. nice. comfy bed..at least for us. quiet.. but we were at end of the hall. room had plenty of space. nice long bathroom counter for toiletries etc. that was outside of tub and potty area. plenty of choices for breakfast. employees friendly. would definitely stay again!!"
Marilyn 1-night trip
Posted 7 days ago
Ramada by Wyndham Sellersburg/Louisville North

Explore a world of travel with Expedia