Top Hotels Near Santo Spirito Hospital in Rome from NZ$212

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13 Nov - 14 Nov
Tomorrow
14 Nov - 15 Nov
This weekend
13 Nov - 15 Nov
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20 Nov - 22 Nov

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Our top choices for Santo Spirito Hospital hotels

A historic building with a cobblestone street, a well-lit entrance, and a car parked nearby.

1. Hotel De' Ricci - Small Luxury Hotels of The World

Hotel De' Ricci - Small Luxury Hotels of The World
4.0 star property
Regola, 0.7 km from Santo Spirito Hospital
10.0 out of 10, Exceptional, (130 reviews)
"Great staff! Amazing Wine List! Great location"
United States
William
The price is NZ$806
includes taxes & fees
14 Dec - 15 Dec
Hotel De' Ricci - Small Luxury Hotels of The World
An outdoor seating area with a table and chairs, a potted plant, and a building entrance.

2. Passpartout Boutique Palace

Passpartout Boutique Palace
0.4 km from Santo Spirito Hospital
9.8 out of 10, Exceptional, (311 reviews)
"Lovely little hotel, brilliant location"
United Kingdom
Joseph
The price is NZ$240
includes taxes & fees
29 Nov - 30 Nov
Passpartout Boutique Palace
A balcony with a table and two chairs, overlooking a building with green shutters and a clear sky.

3. My Rooms in Vatican City

My Rooms in Vatican City
0.6 km from Santo Spirito Hospital
9.8 out of 10, Exceptional, (6 reviews)
"Alessandro is amazing host, and everything was exceptional."
United States
Brighton
The price is NZ$255
includes taxes & fees
1 Dec - 2 Dec
My Rooms in Vatican City
A building entrance with a glass door, a sign reading "CONDOMINIO", and a number "3" on the wall.

4. BePlace Holy See

BePlace Holy See
0.6 km from Santo Spirito Hospital
9.8 out of 10, Exceptional, (6 reviews)
"BePlace Holy See is in an excellent location if youā€™re looking to visit the Vatican and St. Peterā€™s Basilica. There are also several cafes close by."
United States
Landon
The price is NZ$220
includes taxes & fees
16 Nov - 17 Nov
BePlace Holy See
A hallway with a patterned floor, a door with a glass panel, and a hanging light fixture.

5. Domus Giulia

Domus Giulia
Ponte, 0.2 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (201 reviews)
"Great location, service, and clean. We would stay here again."
United States
Oscar
The price is NZ$212
includes taxes & fees
22 Nov - 23 Nov
Domus Giulia
A grand staircase with a wrought iron railing, a dining area with a table and chairs, and a large vase with branches.

6. Allā€™Orologio

Allā€™Orologio
Ponte, 0.4 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (204 reviews)
"The staff are wonderful and very helpful. Location is fantastic, with many shops, restaurants, and sights."
United States
Diane
The price is NZ$276
includes taxes & fees
14 Dec - 15 Dec
Allā€™Orologio
A building facade with multiple windows, a balcony, and a sign for 'Carrefour express'.

7. Passepartout

Passepartout
Parione, 0.6 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (443 reviews)
"Great location Quiet at night Lots of things to do withing a short walking distance Highly recommend this hotel for the value"
Canada
David
The price is NZ$212
includes taxes & fees
13 Dec - 14 Dec
Passepartout
A dining area with a table set for four, featuring yellow chairs and a glass table. A window with a view of buildings and a cactus is visible.

8. Corso Vittorio 308

Corso Vittorio 308
Ponte, 0.3 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (80 reviews)
"We enjoyed our stay. The rooms were clean and comfortable."
United States
Laurie
The price is NZ$310
includes taxes & fees
2 Dec - 3 Dec
Corso Vittorio 308
A hallway with high ceilings, ornate moldings, and large wooden doors.

9. Be Mate Castel Sant'Angelo

Be Mate Castel Sant'Angelo
Ponte, 0.4 km from Santo Spirito Hospital
9.8 out of 10, Exceptional, (52 reviews)
"Nicely renovated apartment with 3 large bedrooms along with a large dining room, living room and a nicely appointed kitchen. Elevator access made moving in and out easy. A\C worked great."
Canada
Christopher
The price is NZ$490
includes taxes & fees
18 Nov - 19 Nov
Be Mate Castel Sant'Angelo
A hotel room with a view of a historic building, a small table with a cup and saucer, and a vase with flowers on a shelf.

10. Charme 308

Charme 308
Ponte, 0.3 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (113 reviews)
"This is one of the best hotels Iā€™ve ever stayed at! The staff were wonderful, and the location was perfect for exploring Venice. I would absolutely recommend it to anyone planning a trip there!"
United States
Phillip
The price is NZ$269
includes taxes & fees
13 Dec - 14 Dec
Charme 308
A balcony with a table set for a meal, including wine, bread, and meat.

11. Le Suite Del Barone

Le Suite Del Barone
Ponte, 0.6 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (480 reviews)
"Had a really great stay, the bed was really comfortable and it was an excellent location!"
United Kingdom
Madelaine
The price is NZ$282
includes taxes & fees
14 Dec - 15 Dec
Le Suite Del Barone
A multi-story building with a classic architectural style, featuring multiple windows and balconies.

12. Velantia Vaticano - Guesthouse

Velantia Vaticano - Guesthouse
3.0 star property
Prati, 0.6 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (13 reviews)
"Very convenient location,very near by Vatican museum , walking distant.a lot of places we can eat , mini market . I like this place , will recommend friend Joana"
United States
Joana
The price is NZ$228
includes taxes & fees
16 Nov - 17 Nov
Velantia Vaticano - Guesthouse
A building with a large wooden door, a small window with a metal grille, and a potted plant in front.

13. Porta Castello Suites

Porta Castello Suites
0.5 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (275 reviews)
"Room was clean and air conditioning worked well. The hotel is near St Peterā€™s Basilica and was in walking distance from many areas. We enjoyed our stay."
United States
Jeannette
The price is NZ$185
includes taxes & fees
15 Nov - 16 Nov
Porta Castello Suites
A cobblestone street with outdoor seating, a chalkboard sign with reception hours, and potted plants.

14. BRAMA by HiSuiteRome

BRAMA by HiSuiteRome
Ponte, 0.6 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (13 reviews)
"The location is superb! Walking distance to everything Rome has to offer. Room clean, private terrace up top to finish the evening. Really enjoyed our stay!"
Canada
Pawel
The price is NZ$262
includes taxes & fees
23 Nov - 24 Nov
BRAMA by HiSuiteRome
A multi-story building with a yellow facade, multiple balconies, and parked cars along the street.

15. Cassiodoro 19

Cassiodoro 19
Prati, 0.7 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (571 reviews)
"Superb location and property manager that tended to each and every need. Strong recommendation"
United States
James A
The price is NZ$256
includes taxes & fees
18 Nov - 19 Nov
Cassiodoro 19
The entrance of Hotel S. Anna with a covered entrance, a staircase leading inside, and a sign indicating the hotel's name.

16. Hotel Sant' Anna

Hotel Sant' Anna
3.0 star property
0.5 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (370 reviews)
"Very convenient to the Vatican and many restaurants on the same street and surrounding streets to choose from."
United States
Sharon
The price is NZ$362
includes taxes & fees
14 Dec - 15 Dec
Hotel Sant' Anna
A modern hotel room with a large bed, a desk with a chair, a glass door leading to a balcony, and a sculpture on the wall.

17. Vatican Style

Vatican Style
0.5 km from Santo Spirito Hospital
9.4 out of 10, Exceptional, (1,006 reviews)
"The location was excellent, rooms were very clean & the breakfast was delicious and plentiful!"
Canada
Marilyn
The price is NZ$248
includes taxes & fees
13 Dec - 14 Dec
Vatican Style
A set of wooden double doors with ornate metal knockers and a small step leading up to them.

18. La Maison dell'Orologio

La Maison dell'Orologio
Ponte, 0.4 km from Santo Spirito Hospital
9.4 out of 10, Exceptional, (327 reviews)
"Check-in was easy. Room was available early, which was helpful after our flight arrived in the morning so we could drop bags and get a shower."
United States
Michael
The price is NZ$158
includes taxes & fees
23 Nov - 24 Nov
La Maison dell'Orologio
A building facade with two arched doorways, one labeled "NOW" and the other with a number "3".

19. Now Apartments

Now Apartments
Ponte, 0.6 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (85 reviews)
"The location was perfect, and we had a very comfortable stay. We really enjoyed our time here and would definitely come back again in the future!"
United States
Hyejeong
The price is NZ$428
includes taxes & fees
17 Nov - 18 Nov
Now Apartments
A hotel room with a large bed, two bedside tables with lamps, a chair, and a view of the outside.

20. Domus Terenzio

Domus Terenzio
Prati, 0.7 km from Santo Spirito Hospital
9.4 out of 10, Exceptional, (63 reviews)
"Wonderful staff"
United States
Aaron
The price is NZ$237
includes taxes & fees
29 Nov - 30 Nov
Domus Terenzio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santo Spirito Hospital Hotel Reviews

A balcony with a table set for breakfast, a potted orchid, and a lamp.
Damaso Hotel

Damaso Hotel

Damaso Hotel
Rome City Centre

10/10 Excellent

From the moment that we arrived we were made to feel special from the staff. Our room was excellent. It even had a view of St Peters if you leaned over the balcony slightly. The rooftop terrace had views all over Rome. It was walkable to most places. The breakfast was amazing. We loved our few days here. Thanks
Australia
Heather
Reviewed September 24, 2026
Damaso Hotel

Frequently Asked Questions

What's the area like around Santo Spirito Hospital?

Santo Spirito Hospital is located in a historic area of Rome known for its stunning cathedral and notable monuments. If you're looking for a convenient place to stay, take a look at the 1955 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay close to Santo Spirito Hospital?

Adjacent to Santo Spirito Hospital, Villa Agrippina Gran MeliĆ” - The Leading Hotels of the World is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 4 restaurants. Other good options close by include Hotel Abruzzi and Vatican Style.

How many hotels can I expect to find close to Santo Spirito Hospital?

Expedia has 1955 hotels and other accommodation options within a mile from Santo Spirito Hospital.

If I need to cancel the hotel reservation for my stay near Santo Spirito Hospital, will I receive a refund?

Yes, you'll find most room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer near Santo Spirito Hospital.

What can I see and do near Santo Spirito Hospital?

You might want to spend some time browsing the exhibits at Castel Sant'Angelo, Cloister of Bramante or Palazzo Spada. Piazza Navona, Pantheon and Trevi Fountain are well-known local landmarks worth a visit. You can check out the local talent at Auditorium Conciliazione, Paul VI Audience Hall and Sistina Theater.

How can I get to Santo Spirito Hospital?

With so many transport options, seeing the area around Santo Spirito Hospital is a breeze. Take advantage of metro transport at Venezia Tram Stop, Arenula-Cairoli Tram Station and Barberini Station. If you want to journey outside of the area, hop aboard a train from Rome Piazzale Flaminio Station, Rome Termini Station or Rome (XRJ-Termini Rail Station).