The best area to stay in Santo Domingo, Extremadura, is the historic centre, particularly around the Plaza Mayor.This area is the heart of Santo Domingo, offering a blend of historic architecture and modern conveniences. The Plaza Mayor itself is a beautiful, arcaded square, often considered one of the finest in Spain. From here, you're just a short walk to the Cathedral of Santa María, the Palacio de los Golfines de Arriba, and a host of traditional tavernas and shops along streets like Calle del Rey. The layout is very pedestrian-friendly, with narrow, winding streets that open up into charming squares.Couples looking for a romantic and culturally rich experience will find the historic centre ideal. You can easily spend your days exploring ancient churches, visiting local museums, and enjoying leisurely meals at restaurants with views of historic buildings. The evening strolls through the illuminated squares are particularly memorable.For solo travellers who appreciate history and convenience, staying near the Plaza Mayor is also an excellent choice.