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Check prices for these dates

Tonight
12 Oct - 13 Oct
Tomorrow
13 Oct - 14 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

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Our top choices for Santiago Este hotels

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.
A spacious lobby with a central water feature, multiple seating areas, and a curved ceiling with hanging lights.
A spacious lobby with modern seating, a central coffee table, and decorative hanging lights.
A restaurant with booths and tables, wooden paneling, and green plants.

1. Hotel Mykonos Panama

Hotel Mykonos Panama
Nuevo Santiago
United States
Ismael
NZ$176
includes taxes & fees
22 Oct - 23 Oct
Hotel Mykonos Panama
A pool surrounded by palm trees and a tiled roof structure.
A tree in a stone planter in a well-lit indoor space with a stone wall and a door in the background.
A building with a curved facade, a balcony with metal railings, and a door with a sign.
A hallway with a glass partition leading to a dining area, a stone wall, and a metal gate with decorative patterns.

2. Hotel Gran David

Hotel Gran David
Santiago
United States
Roxani
NZ$142
includes taxes & fees
13 Oct - 14 Oct
Hotel Gran David
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.
A hotel room with a dark wooden desk, two cushioned chairs, a large mirror, and two table lamps.
A bathroom with a tiled shower wall, a sink, and a towel rack.
A lobby with a reception desk, two armchairs, a sofa, and a table with a lamp.

3. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
Nuevo Santiago
United States
James
NZ$102
includes taxes & fees
13 Oct - 14 Oct
Hotel Plaza Los Tucanes
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.
A multi-story hotel with balconies, a pool, and a reflection in the water.
A spacious dining area with high ceilings, large windows, and natural light. Tables are set with chairs and centerpieces.
A modern bedroom with a large bed, a small table, and a chair. There is a window with curtains and a lamp on the wall.

4. HOTEL VISTA LAGO

HOTEL VISTA LAGO
La Pena
United States
Hedwig
NZ$136
includes taxes & fees
14 Oct - 15 Oct
HOTEL VISTA LAGO
A beach with a wide sandy shore and gentle waves.
A child crossing a rope bridge over water, with a person assisting.
A table set with a variety of food items, including pastries, fruits, and nuts, arranged on a table with a decorative centerpiece.
A building with a thatched roof, a signboard with text, and a parked car.

5. olivias village room

olivias village room
Capellania
NZ$264
includes taxes & fees
13 Oct - 14 Oct
olivias village room
View all properties

Hotels recommended for families in Santiago Este

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.
A spacious lobby with a central water feature, multiple seating areas, and a curved ceiling with hanging lights.
A spacious lobby with modern seating, a central coffee table, and decorative hanging lights.
A restaurant with booths and tables, wooden paneling, and green plants.

Hotel Mykonos Panama

Hotel Mykonos Panama
Nuevo Santiago
NZ$176
includes taxes & fees
22 Oct - 23 Oct
Hotel Mykonos Panama
A pool surrounded by palm trees and a tiled roof structure.
A tree in a stone planter in a well-lit indoor space with a stone wall and a door in the background.
A building with a curved facade, a balcony with metal railings, and a door with a sign.
A hallway with a glass partition leading to a dining area, a stone wall, and a metal gate with decorative patterns.

Hotel Gran David

Hotel Gran David
Santiago
NZ$142
includes taxes & fees
13 Oct - 14 Oct
Hotel Gran David
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.
A hotel room with a dark wooden desk, two cushioned chairs, a large mirror, and two table lamps.
A bathroom with a tiled shower wall, a sink, and a towel rack.
A lobby with a reception desk, two armchairs, a sofa, and a table with a lamp.

Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
Nuevo Santiago
NZ$102
includes taxes & fees
13 Oct - 14 Oct
Hotel Plaza Los Tucanes
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.
A multi-story hotel with balconies, a pool, and a reflection in the water.
A spacious dining area with high ceilings, large windows, and natural light. Tables are set with chairs and centerpieces.
A modern bedroom with a large bed, a small table, and a chair. There is a window with curtains and a lamp on the wall.

HOTEL VISTA LAGO

HOTEL VISTA LAGO
La Pena
NZ$136
includes taxes & fees
14 Oct - 15 Oct
HOTEL VISTA LAGO
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Top Santiago Este Hotel Reviews

Recent Reviews in Santiago Este

Hotel Mykonos Panama

Hotel Mykonos Panama

8/10 Good
"Deben programar realizar limpiezas profundas en las habitaciones. El servicio por parte del staff, fue bueno. Sugiero variar el desayuno de manera intercalada (por días). Esto, para no repetir lo mismo."
Vianka 2-night trip
Posted 7 hours ago
Hotel Mykonos Panama
HOTEL VISTA LAGO

HOTEL VISTA LAGO

10/10 Excellent
"Todo perfecto"
Michele 2-night trip
Posted 3 weeks ago
HOTEL VISTA LAGO
Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes

10/10 Excellent
"Excelente"
Olopilel 1-night trip
Posted 2 months ago
Hotel Plaza Los Tucanes
Hotel Galería

Hotel Galería

10/10 Excellent
"Hay un restaurante en el hotel con desayuno y comida económica y muy sabrosa. La ubicación del hotel es muy céntrica. Es seguro. Tiene centro comercial al lado. Parqueo de carro seguro. Es perfecto para una visita a Santiago."
Lionel 1-night trip
Posted 7 months ago
Hotel Galería

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Frequently asked questions

Where is the best place for a stay in Santiago Este?
Located 14.9 mi (24 km) from the heart of Santiago Este, Hotel Mykonos Panama is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Hotel Gran David and HOTEL VISTA LAGO. See all available top hotels, or vacation rentals in Santiago Este.
What are some of the best holiday rentals that Santiago Este has to offer?
Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.: This holiday home rental outside of Santiago Este is located in a rural location, and offers a garden, air conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchenette with a stovetop, a microwave and a coffee maker, so that you can cook with friends or family. See all vacation rentals in Santiago Este.
If I need to cancel my hotel reservation in Santiago Este, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santiago Este.
What is staying in Santiago Este like?
Travellers to Santiago Este will find plenty to explore and enjoy. There are 17 hotels and other accommodation options in the surrounding area. Find out more about Santiago Este.
What should I see while I'm in Santiago Este?
Places to visit in the wider area include Stella Sierra Regional Museum, Parque Acuatico Italia Guadalupe Panama and Museum of Salt and Sugar. You'll also find Playa Bella Vista and Sarigua National Park in the area. Take a look at what more there is to see and do in Expedia's Santiago Este guide.
What's the weather like in Santiago Este?
The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and December, with an average of 25°C. The rainiest months in Santiago Este are October, August, June and November, with each month seeing an average of 447 mm of rainfall.