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31 Dec - 1 Jan
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1 Jan - 2 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

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Our top choices for Santa Maria hotels

Superior Double Room
Hotel y Cabañas Palomar - Caja los Andes

Hotel y Cabañas Palomar - Caja los Andes

Hotel y Cabañas Palomar - Caja los Andes
2.0 star property
San Felipe
9.4 out of 10, Exceptional, (3)
This welcoming hotel offers both indoor and seasonal outdoor pools in San Felipe. Savour local cuisine at Raíces de los Andes restaurant while enjoying convenient amenities like free parking, 24-hour front desk, and a relaxing terrace.
"Excelente "
Costa Rica
Anonymous traveller
The price is NZ$115
5 Jan - 6 Jan 2026
Hotel y Cabañas Palomar - Caja los Andes
Front of property
Hotel Genova

Hotel Genova

Hotel Genova
2.5 star property
Los Andes
7.2 out of 10, Good, (39)
Cool off in the outdoor pool at this Los Andes hotel offering free WiFi, parking, and continental breakfast. Rooms include refrigerators and microwaves, while a terrace and garden enhance your stay near the Archaeological Museum of the Andes.
"The staff wasn’t very friendly Good place to stay."
United States
Jose
The price is NZ$79
31 Jan - 1 Feb 2026
Hotel Genova
Exterior detail
Inca Hoteles

Inca Hoteles

Inca Hoteles
3.5 star property
Los Andes
9.2 out of 10, Wonderful, (135)
Escape to this inviting hotel in Los Andes featuring an outdoor pool for relaxation and Mikuy restaurant serving international cuisine. Enjoy free breakfast, WiFi, and parking while exploring nearby cultural attractions.
"Restaurant and breakfast buffet are delicious! Rooms were perfect size and very clean. Staff is incredibly friendly and helpful. Easy drive to Portillo to ski! "
United States
CAMERON
The price is NZ$190
5 Jan - 6 Jan 2026
Inca Hoteles
Sauna, hot tub, steam room, hot springs/mineral springs, mud baths
Termas el Corazon

Termas el Corazon

Termas el Corazon
3.0 star property
Los Andes
7.2 out of 10, Good, (10)
Rejuvenate body and soul at this wellness retreat featuring 2 refreshing outdoor pools with poolside bar. Enjoy free breakfast, WiFi, and parking while exploring nearby Museo Antiguo Monasterio del Espíritu Santo.
"Perfect place to relax. Clean, quiet with great food and excellent service"
Canada
Jean-Luc
Termas el Corazon
Interior
Casona El Resguardo

Casona El Resguardo

Casona El Resguardo
3.0 star property
San Esteban
9.6 out of 10, Exceptional, (5)
This serene property offers a seasonal outdoor pool and relaxing spa pool. Enjoy complimentary breakfast, WiFi, and parking, plus garden views. After exploring, grab a bite at the café or sip drinks at the bar.
"Lovely stay in this BnB style hotel. The food was the best part! Excellent chef that makes a special meal nightly considering all dietary restrictions. Location close enough to Portillo Ski resort to drive for daily skiing. Highly recommend. "
United States
Anonymous traveller
The price is NZ$237
11 Jan - 12 Jan 2026
Casona El Resguardo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Maria attractions

El Zaino Dreaming Stones

You can find out about the history of Santa Maria when you stop by El Zaino Dreaming Stones.
See properties

Top Santa Maria Hotel Reviews

Casona El Resguardo

Casona El Resguardo

10/10 Excellent
"Lovely stay in this BnB style hotel. The food was the best part! Excellent chef that makes a special meal nightly considering all dietary restrictions. Location close enough to Portillo Ski resort to drive for daily skiing. Highly recommend. "
Anonymous traveller 3-night trip
Posted 4 months ago
Casona El Resguardo
Enjoy Santiago - Hotel del Valle

Enjoy Santiago - Hotel del Valle

8/10 Good
"Beautiful Scenery, Wonderful Landscape "
Jorge 3-night trip
Posted 7 months ago
Enjoy Santiago - Hotel del Valle

More cheap accommodation in Santa Maria

Hotel Genova

Hotel Genova

523 Las Heras Los Andes Región de Valparaíso
The price is NZ$79 per night from 31 Jan to 1 Feb
NZ$79
31 Jan - 1 Feb 2026
7.2/10 Good! (39 reviews)

Frequently asked questions

Where is the best place to stay in Santa Maria?
Based on our traveller data, Termas Jahuel Hotel & Spa is one of the top choices for your stay. This hotel offers a full-service spa and a restaurant. Two other options for your stay in the area are Hotel Genova and Termas el Corazon. See all available top hotels, or vacation rentals in Santa Maria.
What are some of the best holiday rentals that Santa Maria has to offer?
Boutique-mountain-lodge, near to Santiago de Chile, managed by owners: This holiday home rental outside of Santa Maria offers a balcony, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a fridge and an oven, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. See all vacation rentals in Santa Maria.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Maria.
What's the best accommodation for an all-inclusive stay in Santa Maria?
Termas Jahuel Hotel & Spa is an all-inclusive hotel featuring a full-service spa and a health club, and a favourite with Expedia travellers. See more all-inclusive resorts in Santa Maria.
What is staying in Santa Maria like?
Travellers to Santa Maria will find plenty to explore and enjoy. There are 23 hotels and other accommodation options in the surrounding area. Find out more about Santa Maria.
What is there to see in Santa Maria?
A favourite place to visit is El Zaino Dreaming Stones. You'll also find Termas El Corazón and Museo Antiguo Monasterio del Espíritu Santo in the area. Take a look at what more there is to see and do in Expedia's Santa Maria guide.
What's the seasonal weather like in Santa Maria?
The hottest months are usually January and February, with an average temperature of 20°C, while the coldest months are July and June, with an average of 10°C. Average annual precipitation for Santa Maria is 365 mm.