A tropical island with a beach, clear turquoise waters, and lush greenery.

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Our top choices for Santa Isabel hotels

Ordovician Beach Resort

Ordovician Beach Resort
4.5 star property
Isla Grande
10.0 out of 10, Exceptional, (12 reviews)
"The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed."
Canada
Janet
The price is NZ$852
includes taxes & fees
16 July - 17 July
Ordovician Beach Resort

Ranchos de Chalia

Ranchos de Chalia
3.0 star property
Puerto Lindo
9.8 out of 10, Exceptional, (18 reviews)
"Beautiful grounds and views, nice and helpful staff "
United States
Guillermo
The price is NZ$231
includes taxes & fees
24 July - 25 July
Ranchos de Chalia

Hotel Cocotal

Hotel Cocotal
2.5 star property
Isla Grande
8.6 out of 10, Excellent, (11 reviews)
"Beautiful views, great service "
United States
Israel
Hotel Cocotal

Ciel y Miel

Ciel y Miel
3.0 star property
Cacique
10.0 out of 10, Exceptional, (11 reviews)
"The views from this mountain-top boutique hotel are extraordinary."
United States
Morris
The price is NZ$395
includes taxes & fees
14 July - 15 July
Ciel y Miel

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island
2.0 star property
Narganá
10.0 out of 10, Exceptional, (1 review)
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. "
United States
Ryan
Private Ocean-Front Cabin with private bathroom on San Blas Island

HOTEL ISLA GRANDE

HOTEL ISLA GRANDE
3.0 star property
Isla Grande
4.2 out of 10, (11 reviews)
"This hotel is very run down, and should not be $150/night. Did not have access to running water in our room. Location and beach are its saving graces."
Canada
Kevin
The price is NZ$189
includes taxes & fees
14 July - 15 July
HOTEL ISLA GRANDE

Konsenda San Blas

Konsenda San Blas
2.0 star property
El Llano
10.0 out of 10, Exceptional, (3 reviews)
"wonderful eco lodge in the forest. Easy to reach by car, just on the main road. Paths to walk, excellent meals. A very good option if you need to relax before and after visiting Sab Blas, but worth the trip on its own, beautiful landscape."
Italy
Roberta
The price is NZ$117
includes taxes & fees
14 July - 15 July
Konsenda San Blas

Discovery Gunayar

Discovery Gunayar
2.0 star property
Narganá
6.0 out of 10, (1 review)
"Please fix my Expedia mobile app. It hasn’t worked for several days. The error message says the problem is at Expedia’s end. I have reported this issue by phone but nothing is being done."
United States
Thomas
The price is NZ$198
includes taxes & fees
12 Aug - 13 Aug
Discovery Gunayar

Private wood Cabins on San Blas island - private bathroom

Private wood Cabins on San Blas island - private bathroom
2.0 star property
Narganá
Private wood Cabins on San Blas island - private bathroom

Cabañas Isla Nubesidub San Blas

Cabañas Isla Nubesidub San Blas
2.0 star property
Narganá
The price is NZ$733
includes taxes & fees
26 July - 27 July
Cabañas Isla Nubesidub San Blas

Cabins in Chichime Island

Cabins in Chichime Island
2.0 star property
Narganá
10.0 out of 10, Exceptional, (1 review)
"Endroit magnifique, séjour parfait reposant, nourriture délicieuse avec une petite surprise en fin de séjour "
France
Anonymous traveller
Cabins in Chichime Island

La Semilla Ecolodge

La Semilla Ecolodge
3.5 star property
24 de Diciembre
8.0 out of 10, Very good, (12 reviews)
"We enjoyed our stay at La Semilla immensely. We were treated like royalty by the staff, Daisy and Luce. The hotel is uniquely designed to complement the surrounding rainforest and includes a jacuzzi as well as a sauna. Our room was clean and tastefully designed. We will definitely be returning."
United States
Jacqueline
La Semilla Ecolodge

Cabins on paradise San Blas island

Cabins on paradise San Blas island
2.0 star property
Narganá
The price is NZ$514
includes taxes & fees
13 July - 14 July
Cabins on paradise San Blas island

Cabañas Nalunega San Blas

Cabañas Nalunega San Blas
2.0 star property
Narganá
The price is NZ$678
includes taxes & fees
26 July - 27 July
Cabañas Nalunega San Blas

Trips Guna Yala

Trips Guna Yala
2.0 star property
Narganá
Trips Guna Yala

Hotel El Porvenir

Hotel El Porvenir
2.0 star property
Narganá
Hotel El Porvenir

Cabins in Aguja Island

Cabins in Aguja Island
2.0 star property
Narganá
Cabins in Aguja Island

Cabanas Narasgandub - Naranjo Chico

Cabanas Narasgandub - Naranjo Chico
2.5 star property
Narganá
8.0 out of 10, Very good, (7 reviews)
"Our stay at Cabanas Narasgandub was everything you would expect from a remote and rustic location. You will rise when the rooster crows at the crack of dawn and likely be sleepy shortly after the sun goes down. The cabins are extremely rustic and this location is not for someone expecting a 5 star resort. It's basically camping in the most beautiful scenery. Put aside your need for comfort for a few days and give in to the way of life. It's totally worth it! The community on Naranjo Chico took...
United States
Anonymous traveller
Cabanas Narasgandub - Naranjo Chico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Isabel

Explore pristine beaches along Santa Isabel's coastline where local fishermen can take you to nearby coral reefs for snorkelling. Hike through lush rainforest trails to spot colourful birds, then visit the town's central plaza where vendors sell fresh tropical fruits and handcrafted souvenirs.

A tropical island with a beach, clear turquoise waters, and lush greenery.

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Frequently asked questions

What's the best place to stay in Santa Isabel?
Located 17 mi (27.3 km) from the heart of Santa Isabel, Cocoloco - Catamaran Lagoon 52F SAN BLAS is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Private Ocean-Front Cabin with private bathroom on San Blas Island and Private wood Cabins on San Blas island - private bathroom. See all available top hotels, or vacation rentals in Santa Isabel.
What are some of the best holiday rentals that Santa Isabel has to offer?
Caribbean Haven Of Nature 'Preci Beach': This holiday home rental outside of Santa Isabel is located on the beach, and has an outdoor pool, a fireplace and a BBQ to put you at ease in your new surroundings. It has 4 bedrooms, as well as a kitchen with a fridge, a stovetop and a microwave, so that you can cook with friends or family. It offers a balcony, a garden and a selection of games so that you can immerse yourself in your holiday. See all vacation rentals in Santa Isabel.
If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.
What is staying in Santa Isabel like?
Visitors can enjoy all that Santa Isabel has to offer, including its parks. There are 39 hotels and other accommodation options in the surrounding area. Find out more about Santa Isabel.
What are the top places to visit in Santa Isabel?
Places to visit in the wider area include Museum, Chagres National Park and Porvenir Museum. Take a look at what more there is to see and do in Expedia's Santa Isabel guide.
What's the weather like in Santa Isabel?
The hottest months are usually June and September, with an average temperature of 27°C, while the coldest months are February and March, with an average of 26°C. The rainiest months in Santa Isabel are October, August, July and November, with each month seeing an average of 310 mm of rainfall.

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