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Santa Isabel Holiday Rentals

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Check prices for these dates

In two weeks
23 Oct - 25 Oct
In two months
4 Dec - 6 Dec
In three months
1 Jan - 3 Jan
In four months
29 Jan - 31 Jan

Our top choices for Santa Isabel holiday rentals

A bedroom with a bed, a ceiling fan, a window with curtains, and a view of greenery outside.

1. Mi Verde Horizonte "Panoramic view in Utuado | Nearby river + Nature + WiFi".

Mi Verde Horizonte "Panoramic view in Utuado | Nearby river + Nature + WiFi".
Utuado
10.0 out of 10, Exceptional, (3 reviews)
"Beautiful, clean and the proprietor was extremely helpful in directions to get there; great stay, hope to go back soon."
United States
Santiago C.
The price is NZ$255
includes taxes & fees
20 Oct - 21 Oct
Mi Verde Horizonte "Panoramic view in Utuado | Nearby river + Nature + WiFi".
A kitchen with white cabinets, a wooden ceiling, a dining table with a tray of cookies, and a potted plant.

2. Cozy 2BR, Terrace, AC & WiFi near Tanama River

Cozy 2BR, Terrace, AC & WiFi near Tanama River
Utuado
10.0 out of 10, Exceptional, (2 reviews)
"Definitely would stay again! Casa maya has all you need & in such a beautiful area. We loved it!!!"
United States
Kamryn C.
The price is NZ$542
includes taxes & fees
16 Oct - 17 Oct
Cozy 2BR, Terrace, AC & WiFi near Tanama River
A compact kitchen with a built-in microwave, a dishwasher, and a sink.

3. Caleno Boricua apartment. Modern luxury apartment 5 minutes from the beach

Caleno Boricua apartment. Modern luxury apartment 5 minutes from the beach
Quebradillas
10.0 out of 10, Exceptional, (1 review)
Caleno Boricua apartment. Modern luxury apartment 5 minutes from the beach
A wooden table with a bottle of wine and two glasses on it, set against a white wall with green shutters.

4. Nature's Lodge Escape

Nature's Lodge Escape
Sabana Grande
8.0 out of 10, Very good, (7 reviews)
"Clean and organized, love the mountain view."
United States
Maria V.
The price is NZ$215
includes taxes & fees
13 Oct - 14 Oct
Nature's Lodge Escape
A modern infinity pool with a clear view of the ocean and palm trees.

5. Ventana al Atlantico at Arecibo 681 Ocean Drive

Ventana al Atlantico at Arecibo 681 Ocean Drive
2.5 star property
Arecibo
7.0 out of 10, Good, (294 reviews)
"Everything ok just need some update around the property and more parking and lots of activity around the area Nice view"
United States
Janine
The price is NZ$274
includes taxes & fees
12 Oct - 13 Oct
Ventana al Atlantico at Arecibo 681 Ocean Drive
A spacious living area with a high wooden ceiling, a balcony with a railing, and a modern kitchen in the background.

6. The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico
Adjuntas
9.6 out of 10, Exceptional, (16 reviews)
"Homie place great for relaxing"
United States
Yesenia
The price is NZ$499
includes taxes & fees
14 Oct - 15 Oct
The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico
A compact living space with a kitchenette, a flat-screen TV mounted on the wall, a black leather sofa, and a wooden floor.

7. Colombian Boricua Apartment 5 minutes from the beach luxury

Colombian Boricua Apartment 5 minutes from the beach luxury
Quebradillas
10.0 out of 10, Exceptional, (3 reviews)
"Great place to stay! It was clean, comfortable, and exactly as expected. The host was kind and responsive, and everything went smoothly. I would definitely stay here again and highly recommend it!"
United States
Joshua M.
The price is NZ$125
includes taxes & fees
17 Oct - 18 Oct
Colombian Boricua Apartment 5 minutes from the beach luxury
A coastal property with a wooden deck, white lounge chairs, and a staircase leading to a balcony overlooking the ocean.

8. Casa Colibrí

Casa Colibrí
2.5 star property
Arecibo
4.0 out of 10, (17 reviews)
"The property worked for my stay—I was in town for a funeral and needed something affordable. It has good potential, but several issues made the experience less than ideal: no mirror, no hot water, no Wi‑Fi, and some needed handyman repairs. If these are fixed, it could be a solid place."
United States
Jose
The price is NZ$271
includes taxes & fees
16 Oct - 17 Oct
Casa Colibrí
A bedroom with a bed, a bedside table with a plant, a wardrobe, and an air conditioning unit.

9. Fabulous 2-bedroom house with AC in charming Terranova

Fabulous 2-bedroom house with AC in charming Terranova
Terranova
10.0 out of 10, Exceptional, (6 reviews)
"The house was spotless, in a quiet neighborhood, easy excess to main road, and entertainment, great location everything close by."
United States
Francisco
The price is NZ$195
includes taxes & fees
12 Oct - 13 Oct
Fabulous 2-bedroom house with AC in charming Terranova
A modern living room with a white table, blue sofa, ceiling fan, and a small potted plant.

10. Arecibo Hotel 2105

Arecibo Hotel 2105
2.0 star property
Arecibo
7.8 out of 10, Good, (23 reviews)
"The place was clean and the area was quiet most of the time."
United States
Carlos De La
The price is NZ$265
includes taxes & fees
19 Oct - 20 Oct
Arecibo Hotel 2105
A living room with a sofa, a coffee table, a chair, and a potted plant.

11. The Eden Oasis - A Private Getaway

The Eden Oasis - A Private Getaway
Bajadero
10.0 out of 10, Exceptional, (1 review)
"The home was beautiful and it was close to the beaches and restaurants. We had a wonderful stay and there were several pleasant surprises. The host was very responsive and welcoming!"
United States
Gladys G.
The price is NZ$409
includes taxes & fees
10 Nov - 11 Nov
The Eden Oasis - A Private Getaway
A kitchen counter with a woven basket labeled 'MAKING S'MORE memories,' containing snacks, a bottle, and a glass.

12. Private Romantic Cabin -Heated pool -Nature Escape

Private Romantic Cabin -Heated pool -Nature Escape
San Sebastián
10.0 out of 10, Exceptional, (1 review)
"Peaceful retreat. Felt like I stepped into a book. Just as described. Pictures do not do it justice. Beautiful and tranquil and just what I needed."
United States
Yarissa R.
The price is NZ$658
includes taxes & fees
5 Nov - 6 Nov
Private Romantic Cabin -Heated pool -Nature Escape
A modern living room with a staircase, a black chair, and a painting on the wall.

13. VSS La Puntilla Stylish Coastal Getaway Near Beach

VSS La Puntilla Stylish Coastal Getaway Near Beach
Arecibo
The price is NZ$321
includes taxes & fees
10 Nov - 11 Nov
VSS La Puntilla Stylish Coastal Getaway Near Beach
A beach with clear water, a sandy shore, and a rocky outcrop in the distance.

14. Casa vacacional en Arenales Isabela

Casa vacacional en Arenales Isabela
3.5 star property
Isabela
9.0 out of 10, Wonderful, (50 reviews)
"The property was nice and clean quiet area had everything included inside the house sent you air and the bedrooms were nice"
United States
Jaime
The price is NZ$394
includes taxes & fees
13 Oct - 14 Oct
Casa vacacional en Arenales Isabela
A window with a view of the ocean and a palm tree.

15. Cozy Apartment: Wake to Ocean Waves

Cozy Apartment: Wake to Ocean Waves
Hato Abajo
10.0 out of 10, Exceptional, (6 reviews)
"This was a great place to stay. Everything was as described, and we felt comfortable the whole time. The host’s communication was excellent, very responsive, friendly, and made check-in/check-out super easy. Highly recommend!"
United States
Wendelina L.
The price is NZ$360
includes taxes & fees
10 Nov - 11 Nov
Cozy Apartment: Wake to Ocean Waves
A neatly arranged bedroom with a bed, a bedside table with a lamp, and a chair.

16. Boricua 3 | Cozy Eco-Stay w/ WiFi + A/C

Boricua 3 | Cozy Eco-Stay w/ WiFi + A/C
Rio Pietro
The price is NZ$390
includes taxes & fees
11 Oct - 12 Oct
Boricua 3 | Cozy Eco-Stay w/ WiFi + A/C
Spa

17. Tropical Studio Boutique - Cerca de Gozalandia

Tropical Studio Boutique - Cerca de Gozalandia
Hato Arriba
10.0 out of 10, Exceptional, (1 review)
"Ok"
United States
Wilfredo
Tropical Studio Boutique - Cerca de Gozalandia
A neatly made bed with white bedding, a dark headboard, and a bedside table with a lamp and a digital clock.

18. Cozy Yauco Studio | A/C + WiFi · Boricua 2

Cozy Yauco Studio | A/C + WiFi · Boricua 2
Yauco
The price is NZ$392
includes taxes & fees
11 Oct - 12 Oct
Cozy Yauco Studio | A/C + WiFi · Boricua 2
A modern building with a sign reading "Isabela's INNY HOUSE."

19. Cozy Tiny House for Couples or Families – Peaceful Isabela Retreat

Cozy Tiny House for Couples or Families – Peaceful Isabela Retreat
Isabela
10.0 out of 10, Exceptional, (12 reviews)
"Lively place.. very clean. I really enjoyed my stay! Highly recommend.."
United States
Lurdes R.
The price is NZ$255
includes taxes & fees
9 Nov - 10 Nov
Cozy Tiny House for Couples or Families – Peaceful Isabela Retreat
A modern building exterior with a potted plant, a door, and two illuminated wall fixtures.

20. Executive Studio 3 min beach,A/C, safety and parking

Executive Studio 3 min beach,A/C, safety and parking
Arecibo
10.0 out of 10, Exceptional, (3 reviews)
"I truly enjoyed my stay at this property. The apartment was clean, well-equipped, and conveniently located just 3 minutes from the beach.Joel, thanks for being such a great host and for your attentiveness throughout my stay. I highly recommend this property and would definitely stay here again."
United States
ANITA C.
Executive Studio 3 min beach,A/C, safety and parking
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Isabel Hotel Reviews

Hacienda Villa Sotomayor

Hacienda Villa Sotomayor

8/10 Good
"El desayuno No muy Bueno y Perros en la propiedad que molestan y el camino no muy bueno."
Angel L 2-night trip
Posted 5 hours ago
Hacienda Villa Sotomayor

Find out more about Santa Isabel

You always said you would go on a dream holiday someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannonball into the deep end. Go ahead, unplug and unwind in style. When you book one of our Santa Isabel holiday rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your holiday just got upgraded.

As much as you love your vacation rental, it’s always good to get out and explore to soak up Santa Isabel. Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in Santa Isabel. Seeing all the best attractions is bound to make you fall in love with Santa Isabel. Who knows, you may even be tempted to extend your stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. 

It’s your escape so why share it? You deserve your own slice of paradise. Booking your holiday rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in Santa Isabel short-term rentals, that won’t be hard to do.

Frequently asked questions

Are there holiday rentals in Santa Isabel?

Yes, there are holiday rentals close to the most popular sights in Santa Isabel, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santa Isabel has to offer?

3-Bedroom House in Quebradillas: This holiday home rental outside Santa Isabel is located near the airport, and has a terrace, a garden and free WiFi to put you at ease in your new surroundings. This holiday rental also comes with free parking to give you added peace of mind.

What can I see and do in Santa Isabel?

Explore the area and family-friendly sights such as Maricao Fish Hatchery, or get out into nature at a spot like Tanamá River. Camuy River Cave Park and Lago Garzas are a couple of places you'll find in the wider area.

What are holiday rentals like in Santa Isabel?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santa Isabel. Holiday rentals offer extras such as hot tubs, fire pits and patios so you'll be comfy for your stay. If you're concerned about a sanitised environment, a holiday rental can offer a sense of privacy away from shared hotel lifts and busy concierge desks while still allowing you to travel. You'll also have more space in a holiday rental than in a traditional hotel, which makes a holiday rental a popular choice for family trips.