Santa Cruz Holidays
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to NZ$2,400 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Santa Cruz Holiday
Our pick of the best Santa Cruz Hotel Deals
Santa Cruz Plaza
Plaza De Armas 286 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
The price is NZ$218 per night from 24 May to 25 May
NZ$218
24 May - 25 May
Hotel Vendimia Parador
Camino Los Boldos SN Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
The price is NZ$140 per night from 8 June to 9 June
NZ$140
8 June - 9 June
9.6/10 Exceptional! (85 reviews)
"I had a wonderful experience at this hotel. The location is fantastic—central and convenient to everything I wanted to see. The room was spotless and well-maintained, which I really appreciated. But what truly sets this place apart is the staff. From the front desk to the housekeeping team, everyone ...
Reviewed on 1 Apr 2026
La Perla Hotel
El Rosal, Parcela 4, Lote A, Capellanía Santa Cruz O'Higgins
The price is NZ$141 per night from 21 May to 22 May
NZ$141
21 May - 22 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Cruz
Lapostolle Clos Apalta Winery
You can enjoy a tasting or tour at Lapostolle Clos Apalta Winery during your travels to Santa Cruz. While in this relaxing area, you can savour the wineries and restaurants.
What to do in Santa Cruz
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
