Search Santa Cruz hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
29 May - 31 May
Next weekend
5 Jun - 7 Jun

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Cruz hotels

Exterior

Linda Vista Cabins

Linda Vista Cabins
3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (18 reviews)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
The price is NZ$92
includes taxes & fees
26 May - 27 May
Linda Vista Cabins
Triple Room, 1 King Bed with Sofa bed, Mountain View

Luxury Canyon Suites

Luxury Canyon Suites
2.0 star property
Alto Boquete
7.2 out of 10, Good, (7 reviews)
"New place, still developing "
United States
Amanda
The price is NZ$168
includes taxes & fees
4 June - 5 June
Luxury Canyon Suites
Dining

Hotel Finca Lerida

Hotel Finca Lerida
3.0 star property
Los Naranjos
8.8 out of 10, Excellent, (201 reviews)
"Great place"
United States
Roberto
The price is NZ$276
includes taxes & fees
26 May - 27 May
Hotel Finca Lerida
Premium Cabin | Terrace/patio

Los Quetzales Ecolodge & Spa

Los Quetzales Ecolodge & Spa
3.0 star property
Cerro Punta
8.8 out of 10, Excellent, (36 reviews)
"Staff was amazing, local foods excellent. Perfect location for hiking the vertical farms and bird watching!"
United States
David
The price is NZ$202
includes taxes & fees
26 May - 27 May
Los Quetzales Ecolodge & Spa
Double Room, Garden View | Property grounds

Little Italy B&B

Little Italy B&B
3.0 star property
Tijeras
9.4 out of 10, Exceptional, (53 reviews)
"We loved the breakfast which included fresh fruit. Erick and his wife Jessica couldn’t have been more accommodating. We highly recommend this B&B to anyone coming to the area."
United States
Stephan
The price is NZ$75
includes taxes & fees
26 May - 27 May
Little Italy B&B
Family House, 2 Bedrooms, Garden View

Casa Little Italy

Casa Little Italy
3.0 star property
Tijeras
6.0 out of 10, (1 review)
"Didn't accept credit card payment "
Mexico
ANGELO
The price is NZ$130
includes taxes & fees
26 May - 27 May
Casa Little Italy
Spa

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals
3.0 star property
Volcan
8.2 out of 10, Very good, (259 reviews)
"nice classy place. with beautiful grounds.."
Canada
Gordon J
The price is NZ$213
includes taxes & fees
23 June - 24 June
Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals
Deluxe Double Room

Los Brezos Boutique Hotel

Los Brezos Boutique Hotel
3.5 star property
Volcan
9.4 out of 10, Exceptional, (30 reviews)
"Excellent choice for your stay in Volcan. I stayed for 2 nights as solo traveler. Great staff and management. Everyone was helpful and friendly. Volcan is a great base for exploring Cerro Punto region for a day or 2. I highly recommend this hotel. "
United States
Jay
The price is NZ$223
includes taxes & fees
27 May - 28 May
Los Brezos Boutique Hotel
Exterior

Hostal Victoria Volcán Chiriquí S. A.

Hostal Victoria Volcán Chiriquí S. A.
2.0 star property
Nueva California
9.0 out of 10, Wonderful, (10 reviews)
"Hostal Victoria was a simple and down-to-earth Hostal. The entire staff were friendly, kind, and helpful. Good value for a budget place to stay. "
United States
John
The price is NZ$85
includes taxes & fees
26 May - 27 May
Hostal Victoria Volcán Chiriquí S. A.
Exterior

Hotel Dos Rios

Hotel Dos Rios
3.0 star property
Nueva California
8.6 out of 10, Excellent, (84 reviews)
"Beautiful garden "
Canada
Kevin
The price is NZ$161
includes taxes & fees
26 May - 27 May
Hotel Dos Rios
Property entrance

Hotel Las Canarias

Hotel Las Canarias
3.0 star property
Paso Canoas
The price is NZ$83
includes taxes & fees
26 May - 27 May
Hotel Las Canarias
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Luxury Canyon Suites

Luxury Canyon Suites

8/10 Good
"Very private, and clean, very nice rooms"
Hilary 4-night trip
Posted 4 days ago
Luxury Canyon Suites

More cheap accommodation in Santa Cruz

Hostal Victoria Volcán Chiriquí S. A.

Hostal Victoria Volcán Chiriquí S. A.

Volcan Chiriquí Nueva California Chiriquí
The price is NZ$85 per night from 26 May to 27 May
NZ$85
26 May - 27 May
includes taxes & fees
9/10 Wonderful! (10 reviews)

Frequently asked questions

Where is the best place to stay in Santa Cruz?
Located 12.3 mi (19.8 km) from the heart of Santa Cruz, Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals is a top choice for your stay, based on our traveller data. Other good options for your visit to the area are Hotel Finca Lerida and Casa Grande Bambito Resort. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Potrerillos Ranch close to Boquete: This holiday home rental outside of Santa Cruz is located in the mountains, and has a balcony, a garden and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! The majority of room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz will definitely find plenty to explore and enjoy. There are 55 hotels and other accommodation options in the surrounding area. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Places to visit in the wider area include Las Cavernas de Corredores, Barriles and Paradise Tropical Garden. You'll also find Área Silvestre Protegida Lagunas de Volcán and Canyon Macho de Monte in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
What's the seasonal weather in Santa Cruz?
The hottest months are usually March and February, with an average temperature of 26°C, while the coldest months are January and December, with an average of 25°C. The rainiest months in Santa Cruz are October, November, August and July, with each month seeing an average of 752 mm of rainfall.