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The best area to stay in Santa Cruz Do Douro is along the Douro River, particularly in and around the village of Santa Cruz do Douro itself.This area offers direct access to the river and its stunning views, which are a major draw for visitors. You'll find a selection of high-quality guesthouses and hotels located into the hillsides, many with terraces overlooking the water. The main road, EN222, generally follows the river, connecting the small villages and vineyards.For couples seeking a romantic getaway, staying right by the Douro River is ideal. Many accommodations here offer private balconies, infinity pools, and opportunities for wine tastings at nearby quintas (wine estates). The serene setting and beautiful scenery provide a great backdrop for relaxation and reconnecting.Families will also appreciate the riverfront locations, especially those with properties offering amenities like swimming pools and spacious grounds.