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Top hotels and accommodation in San Francisco

Hotel Mykonos Panama
Relax by the pool with a refreshing drink and a good book.

Hotel Mykonos Panama

3.5 star property
8.8 out of 10, Excellent, (521)
"Great location and service."
The price is NZ$144
includes taxes & fees
4 Aug - 5 Aug
Hotel Mykonos Panama
Hotel Galería
Relax by the pool in a tranquil setting, complete with a gazebo and comfortable lounge seating.

Hotel Galería

3.0 star property
8.4 out of 10, Very good, (192)
"SC"
The price is NZ$117
includes taxes & fees
30 July - 31 July
Hotel Galería
Hotel Gran David
Relax by the serene pool surrounded by lush palm trees and lounge chairs.

Hotel Gran David

3.5 star property
8.4 out of 10, Very good, (316)
"Excellent place for family"
Hotel Gran David
HOTEL VISTA LAGO
Relax by the serene pool surrounded by lush greenery and a variety of plants, with a pavilion offering shade and a slide for fun.

HOTEL VISTA LAGO

3.0 star property
9.2 out of 10, Wonderful, (65)
"Very clean, food was 10/10 "
The price is NZ$140
includes taxes & fees
30 July - 31 July
HOTEL VISTA LAGO
Hotel Anachoreo
Enjoy a meal amidst a serene garden setting with a table set for a delicious meal.

Hotel Anachoreo

3.0 star property
9.4 out of 10, Exceptional, (34)
"Excellent accommodation: Room, grounds, and common area are beautifully decorated and spotless clean. Staff were friendly & helpful. Only problem was issue with hot water heater the day of our stay. "
Hotel Anachoreo
La Qhia Eco Retreat
Terrace/patio

La Qhia Eco Retreat

2.5 star property
8.0 out of 10, Very good, (18)
"Very noisy due to neighbouring roosters & dogs at night. Food good & easy access. "
La Qhia Eco Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about San Francisco

Check out Parque Acuatico Italia Guadalupe Panama and Parque Nacional Cerro Hoya—just a couple of the sights around San Francisco.

See all hotels in San Francisco

Top San Francisco Hotel Reviews

HOTEL VISTA LAGO

HOTEL VISTA LAGO

10/10 Excellent
"Really a wonderful surprise and a beautiful and relaxing hotel. Food was well prices and super delicious:)"
walter 1-night trip
Posted 8 days ago
HOTEL VISTA LAGO

Frequently asked questions

What's the best place for a stay in San Francisco?

Hotel Gran David, located 9.5 mi (15.4 km) from the heart of San Francisco, is a top choice for your stay, based on our traveller data. Other good options for your stay in the area are Hotel Mykonos Panama and HOTEL VISTA LAGO. See all available top hotels, or vacation rentals in San Francisco.

What are some of the best holiday rentals that San Francisco has to offer?

Cabana Vergara Santa Fe: This holiday home rental outside of San Francisco is equipped with a patio, air conditioning and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a fridge, a stovetop and kitchenware. See all vacation rentals in San Francisco.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! You'll find that most room reservations are refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in San Francisco.

What is staying in San Francisco like?

Visitors to San Francisco will definitely find plenty to explore and enjoy. There are 16 hotels and other accommodation options in the surrounding area. Find out more about San Francisco.

What should I see while I'm in San Francisco?

Places to visit in the wider area include Laguna de La Yeguada, Parque Acuatico Italia Guadalupe Panama and Parque Nacional Cerro Hoya. You'll also find Catedral of Santiago Apostol and Los Pozos Termales in the area. Take a look at what more there is to see and do in Expedia's San Francisco guide.

What's the seasonal weather like in San Francisco?

The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and December, with an average of 25°C. The rainiest months in San Francisco are October, August, June and November, with each month seeing an average of 447 mm of rainfall.