
Roxboro Holiday Rentals
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Our top choices for Roxboro holiday rentals

1. 4 Blocks from UPTOWN, all new renovation, SUPER NICE!
4 Blocks from UPTOWN, all new renovation, SUPER NICE!
2. Fortress of Solitude
Fortress of Solitude
3. 25-Acre Oxford Retreat l Waterfront Cabin + Hot Tub
25-Acre Oxford Retreat l Waterfront Cabin + Hot Tub
4. The Lake House: Dock|Marine Hammock|Screen Porch
The Lake House: Dock|Marine Hammock|Screen Porch
5. King Bed Non-Smoking
King Bed Non-Smoking
6. Hyco Hospitable, 2026 Reno, Sleeps 8, Water Views!
Hyco Hospitable, 2026 Reno, Sleeps 8, Water Views!
7. Stunning 25-Acre Oxford Escape l Waterfront l BBQ
Stunning 25-Acre Oxford Escape l Waterfront l BBQ
8. Charming 4-bedroom 3-bath house on beautiful Hyco Lake with boat dock.
Charming 4-bedroom 3-bath house on beautiful Hyco Lake with boat dock.
9. Dog-Friendly Lakeside Escape w/ Hammock & Fire Pit
Dog-Friendly Lakeside Escape w/ Hammock & Fire Pit
10. Studio near Duke Univ, Hospital & downtown
Studio near Duke Univ, Hospital & downtown
11. Stylish-Modern Open Concept Studio In The Hearth Of Durham NC
Stylish-Modern Open Concept Studio In The Hearth Of Durham NC
12. Hyco Lake Glass Retreat + Hot Tub
Hyco Lake Glass Retreat + Hot Tub
13. The Country Estate #1 Tranquil 1BR estate perfect for a relaxing getaway.
The Country Estate #1 Tranquil 1BR estate perfect for a relaxing getaway.
14. 2 Queen Beds Non-Smoking
2 Queen Beds Non-Smoking
15. Not Your Average Stay” +Glow Room by 9th St, Duke, Alexa,Games & WiFi + NEW! 2bd
Not Your Average Stay” +Glow Room by 9th St, Duke, Alexa,Games & WiFi + NEW! 2bd
16. 10 minutes from VIR. Great bass fishing! Rustic cottage on large private pond.
10 minutes from VIR. Great bass fishing! Rustic cottage on large private pond.
17. Charming 3-bedroom house, in pleasant North Durham
Charming 3-bedroom house, in pleasant North Durham
18. Modern And Cozy House In The Heart Of Hillsborough
Modern And Cozy House In The Heart Of Hillsborough
19. *Pet Friendly* Charming-Single story | Fenced Yard, Outdoor Dining, Near Duke
*Pet Friendly* Charming-Single story | Fenced Yard, Outdoor Dining, Near Duke
20. 10min to Cameron | Near Duke Hospital, Univ, Dtwn
10min to Cameron | Near Duke Hospital, Univ, DtwnFind holiday rentals that suit your style
Top Roxboro Hotel Reviews

Comfort Inn & Suites Durham near Duke University
Find out more about Roxboro
You always said you would go on a dream holiday someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannonball into the deep end. Go ahead, unplug and unwind in style. When you book one of our Roxboro holiday rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your holiday just got upgraded.
As much as you love your vacation rental, it’s always good to get out and explore to soak up Roxboro. Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in Roxboro. Seeing all the best attractions is bound to make you fall in love with Roxboro. Who knows, you may even be tempted to extend your stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.
It’s your escape so why share it? You deserve your own slice of paradise. Booking your holiday rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in Roxboro short-term rentals, that won’t be hard to do.



































































