Top Hotels Near Roswell Park Comprehensive Cancer Center in Buffalo from NZ$260

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15 Nov - 16 Nov
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Our top choices for Roswell Park Comprehensive Cancer Center hotels

A grand staircase with ornate wood paneling and patterned carpet.

1. InnBuffalo off Elmwood

InnBuffalo off Elmwood
2.5 star property
Elmwood Village, 2.5 km from Roswell Park Comprehensive Cancer Center
10.0 out of 10, Exceptional, (225 reviews)
"Friendly staff, clean and amazing breakfast"
Germany
Terese
The price is NZ$261
includes taxes & fees
29 Nov - 30 Nov
InnBuffalo off Elmwood
A historic building with a prominent tower and a traditional brick facade.

2. Buffalo Harmony House

Buffalo Harmony House
4.5 star property
Allentown, 1.2 km from Roswell Park Comprehensive Cancer Center
10.0 out of 10, Exceptional, (58 reviews)
"Beautiful place. Great breakfasts. Wonderful staff."
United States
John
The price is NZ$682
includes taxes & fees
16 Nov - 17 Nov
Buffalo Harmony House
A spacious room with a large wooden table, several chairs, a sofa, and two chandeliers.

3. The Edward Hotel

The Edward Hotel
3.0 star property
Elmwood Village, 2.3 km from Roswell Park Comprehensive Cancer Center
9.6 out of 10, Exceptional, (272 reviews)
"Great place!"
United States
Noe
The price is NZ$353
includes taxes & fees
19 Nov - 20 Nov
The Edward Hotel
A bedroom with a four-poster bed, a large window with a view of a body of water, and a flat-screen TV mounted on the wall.

4. Buffalo Marriott at LECOM HARBORCENTER

Buffalo Marriott at LECOM HARBORCENTER
3.5 star property
Downtown Buffalo, 2.6 km from Roswell Park Comprehensive Cancer Center
9.4 out of 10, Exceptional, (992 reviews)
"Great stay"
United States
Stephen
The price is NZ$531
includes taxes & fees
23 Nov - 24 Nov
Buffalo Marriott at LECOM HARBORCENTER
A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

5. The Mansion On Delaware Ave

The Mansion On Delaware Ave
4.0 star property
Allentown, 0.8 km from Roswell Park Comprehensive Cancer Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Great place to stay!"
United States
Marilyn
The price is NZ$409
includes taxes & fees
17 Nov - 18 Nov
The Mansion On Delaware Ave
A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

6. Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel
5.0 star property
Buffalo Theater District, 1.3 km from Roswell Park Comprehensive Cancer Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Loved it, we actually rerouted our return trip home to stay here again :)"
United States
John
The price is NZ$537
includes taxes & fees
14 Dec - 15 Dec
Curtiss Hotel, an Ascend Collection Hotel
A black sign with gold lettering for 'Buffalo Guesthouse' at 531 Franklin Street.

7. Buffalo Guesthouse

Buffalo Guesthouse
4.0 star property
Allentown, 0.5 km from Roswell Park Comprehensive Cancer Center
9.4 out of 10, Exceptional, (233 reviews)
"Excellent location and service."
United States
Jose
The price is NZ$343
includes taxes & fees
16 Nov - 17 Nov
Buffalo Guesthouse
A modern building with a Starbucks on the ground floor, featuring large windows and a flat roof.

8. Residence Inn by Marriott Buffalo Downtown

Residence Inn by Marriott Buffalo Downtown
3.0 star property
Allentown, 0.7 km from Roswell Park Comprehensive Cancer Center
9.2 out of 10, Wonderful, (390 reviews)
"Spacious room, friendly staff, and great location in Buffalo."
United States
Karen
The price is NZ$393
includes taxes & fees
23 Nov - 24 Nov
Residence Inn by Marriott Buffalo Downtown
A spacious lobby with modern furniture, large windows, and a high ceiling with exposed beams.

9. The Westin Buffalo

The Westin Buffalo
4.0 star property
Buffalo Theater District, 1.2 km from Roswell Park Comprehensive Cancer Center
9.2 out of 10, Wonderful, (438 reviews)
"Nice brunch"
United States
Sarah
The price is NZ$575
includes taxes & fees
23 Nov - 24 Nov
The Westin Buffalo
A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

10. Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown
3.0 star property
Downtown Buffalo, 0.2 km from Roswell Park Comprehensive Cancer Center
9.0 out of 10, Wonderful, (1,903 reviews)
"Was a great stay"
United States
Sara
The price is NZ$333
includes taxes & fees
23 Nov - 24 Nov
Wyndham Garden Buffalo Downtown
A multi-story hotel with a modern design, featuring a prominent entrance with a covered walkway and a courtyard.

11. Courtyard Buffalo Downtown / Canalside

Courtyard Buffalo Downtown / Canalside
3.0 star property
Downtown Buffalo, 2.4 km from Roswell Park Comprehensive Cancer Center
9.0 out of 10, Wonderful, (1,002 reviews)
"Great location, super friendly staff, great parking -bonus they have a fridge in the room and a microwave"
Canada
Justin
The price is NZ$366
includes taxes & fees
6 Dec - 7 Dec
Courtyard Buffalo Downtown / Canalside
A hotel with a prominent red sign, large windows, and a parking lot with multiple cars.

12. Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown
2.5 star property
Buffalo Theater District, 1.3 km from Roswell Park Comprehensive Cancer Center
8.8 out of 10, Excellent, (1,001 reviews)
"close to all the attractions"
Canada
Scott
The price is NZ$357
includes taxes & fees
23 Nov - 24 Nov
Hampton Inn & Suites Buffalo Downtown
A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

13. Best Western on the Avenue

Best Western on the Avenue
2.5 star property
Allentown, 0.7 km from Roswell Park Comprehensive Cancer Center
8.8 out of 10, Excellent, (1,006 reviews)
"Great place to stay."
United States
James
The price is NZ$302
includes taxes & fees
14 Dec - 15 Dec
Best Western on the Avenue
A hotel lobby with seating areas, a reception desk, and large windows overlooking the street.

14. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
2.5 star property
Buffalo Theater District, 1.1 km from Roswell Park Comprehensive Cancer Center
8.6 out of 10, Excellent, (1,003 reviews)
"We liked our stay."
United States
Daniel
The price is NZ$237
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
A hotel entrance with a glass door featuring a decorative metal design and a welcoming message.

15. Hilton Garden Inn Buffalo Downtown

Hilton Garden Inn Buffalo Downtown
3.0 star property
Buffalo Theater District, 1.5 km from Roswell Park Comprehensive Cancer Center
8.6 out of 10, Excellent, (1,000 reviews)
"The staff was always there and willing to help. Great customer service!!"
United States
Brianne
The price is NZ$262
includes taxes & fees
23 Nov - 24 Nov
Hilton Garden Inn Buffalo Downtown
A casino interior with slot machines, a large illuminated pillar, and comfortable seating areas.

16. Summer Street Guest House

Summer Street Guest House
3.0 star property
Bryant, 1.3 km from Roswell Park Comprehensive Cancer Center
9.6 out of 10, Exceptional, (4 reviews)
"Charles greeted us upon arrival and took us on a tour of his beautiful house. It was magnificent. Spacious and well-appointed. A terrific stay!"
Canada
Anthony
The price is NZ$827
includes taxes & fees
22 Nov - 23 Nov
Summer Street Guest House
A modern hotel with a curved glass facade, a central staircase, and a well-lit interior.

17. Embassy Suites Buffalo

Embassy Suites Buffalo
3.5 star property
Buffalo Theater District, 1.3 km from Roswell Park Comprehensive Cancer Center
8.4 out of 10, Very good, (1,001 reviews)
"I enjoyed my stay"
United States
Laporsche
The price is NZ$357
includes taxes & fees
29 Nov - 30 Nov
Embassy Suites Buffalo
A lobby with a staircase, seating area, and a view of the outdoors.

18. Lenox Hotel and Suites

Lenox Hotel and Suites
2.5 star property
Allentown, 0.8 km from Roswell Park Comprehensive Cancer Center
8.2 out of 10, Very good, (138 reviews)
"Enjoyed our stay"
United States
Thomas
The price is NZ$164
includes taxes & fees
6 Dec - 7 Dec
Lenox Hotel and Suites
An indoor swimming pool with clear glass walls, a wooden wall, and a view of buildings outside.

19. Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center
3.5 star property
Buffalo Theater District, 1.3 km from Roswell Park Comprehensive Cancer Center
8.2 out of 10, Very good, (1,851 reviews)
"Wonderful staff, easy check-in and check-out, great location!"
United States
Eric
The price is NZ$321
includes taxes & fees
19 Nov - 20 Nov
Hyatt Regency Buffalo / Hotel and Conference Center
The facade of Hotel at the Lafayette with a classic architectural style, large windows, and a prominent entrance.

20. Hotel at the Lafayette Trademark Collection by Wyndham

Hotel at the Lafayette Trademark Collection by Wyndham
3.5 star property
Buffalo Theater District, 1.6 km from Roswell Park Comprehensive Cancer Center
8.2 out of 10, Very good, (1,005 reviews)
"Great staff and location."
United States
Thomas
The price is NZ$286
includes taxes & fees
29 Nov - 30 Nov
Hotel at the Lafayette Trademark Collection by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Roswell Park Comprehensive Cancer Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A grand staircase with ornate wood paneling and patterned carpet.
InnBuffalo off Elmwood
2.5 star property
10.0
Exceptional
225 reviews
View
A historic building with a prominent tower and a traditional brick facade.
Buffalo Harmony House
4.5 star property
10.0
Exceptional
58 reviews
View
A spacious room with a large wooden table, several chairs, a sofa, and two chandeliers.
The Edward Hotel
3.0 star property
9.6
Exceptional
272 reviews
View
A bedroom with a four-poster bed, a large window with a view of a body of water, and a flat-screen TV mounted on the wall.
Buffalo Marriott at LECOM HARBORCENTER
3.5 star property
9.4
Exceptional
992 reviews
View
A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.
The Mansion On Delaware Ave
4.0 star property
9.4
Exceptional
1,003 reviews
View

Hotels recommended for families near Roswell Park Comprehensive Cancer Center

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown
3.0 star property
Downtown Buffalo
9.0 out of 10, Wonderful, (1,903)
The price is NZ$333
includes taxes & fees
23 Nov - 24 Nov
Wyndham Garden Buffalo Downtown

Other attractions near Roswell Park Comprehensive Cancer Center

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

8.2/10 (144 reviews)
You can browse the exhibits at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, a museum with a storied past, during your travels to Buffalo. Experience the area's entertainment choices and acclaimed theatre scene.
See properties

Top Roswell Park Comprehensive Cancer Center Hotel Reviews

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.
The Mansion On Delaware Ave

The Mansion On Delaware Ave

The Mansion On Delaware Ave
Downtown Buffalo

10/10 Excellent

Lovely property with good service
Australia
Michael
Reviewed October 24, 2025
The Mansion On Delaware Ave

Frequently Asked Questions

What's the area like around Roswell Park Cancer Institute?

Roswell Park Cancer Institute is located in a historic area of Buffalo known for its popular theatre scene. If you're looking for a convenient place to stay, take a look at the 71 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay close to Roswell Park Cancer Institute?

Adjacent to Roswell Park Cancer Institute, Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices close by include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels will I be able to find near Roswell Park Cancer Institute?

Expedia has 71 hotels and other accommodation options within a mile from Roswell Park Cancer Institute.

If I need to cancel the hotel reservation for my stay near Roswell Park Cancer Institute, will I receive a refund?

Yes! The majority of hotel bookings are refundable if you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to view top deals close to Roswell Park Cancer Institute.

What can I see and do near Roswell Park Cancer Institute?

You might want to spend some time browsing the exhibits at Buffalo Museum of Science, Buffalo and Erie County Naval and Military Park or Buffalo AKG Art Museum. Statler Tower, Buffalo Central Terminal and Peace Bridge are monuments to see when you're exploring the area around Roswell Park Cancer Institute. You can catch a show at Kleinhans Music Hall, Town Ballroom and Road Less Traveled Productions.

How can I get to Roswell Park Cancer Institute?

With so many transport options, seeing the area around Roswell Park Cancer Institute is a breeze. Take advantage of metro transport at Fountain Plaza Station, Lafayette Square Station and Church Station. If you're taking a train into town, Buffalo-Exchange Street Station is the closest stop to Downtown Buffalo.