Murphysboro Holidays
Book a Hotel + Flight or Car together to unlock savings
Photo by Southernmost Illinois Tourism Bureau
- Plan, book, travel with confidence
- Better togetherSave up to NZ$616 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Murphysboro Holiday
Our pick of the best Murphysboro Hotel Deals
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
120 MUDDY MONSTER ROAD Murphysboro IL
Fully refundable
The price is NZ$204 per night from 22 Feb to 23 Feb
NZ$204
22 Feb - 23 Feb
includes taxes & fees
9.4/10 Exceptional! (523 reviews)
Friendly staff, wonderful breakfast, quiet. GREAT PLACE TO STAY!!
Reviewed on 8 Feb 2026
On the Lake & Wine Trail & a Perfect Getaway for 16+ With an ADA Suite!
Murphysboro IL
9.8/10 Exceptional! (16 reviews)
We had a lovely stay! The space was perfect for our family gathering. Our host was very responsive and welcoming. The home has a great location and we were able to enjoy some lovely hikes in the Shawnee and delicious BBQ in Murphysboro!
Reviewed on 29 Dec 2025
5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING
Murphysboro IL
10/10 Exceptional! (20 reviews)
The host was very informative and shared any information we would need. She was quick to respond when we had a question.The cabin is an excellent place to sit back and relax. Had everything we needed. We actually looked to book again for the summer so we could enjoy the pond and pool. Everything ...
Reviewed on 6 Feb 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
