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Our top choices for Mesopotamia hotels

1. To Spiti tis Sofias

To Spiti tis Sofias
Kastoria
10.0 out of 10, Exceptional, (2 reviews)
"Very nice and warm welcome from the owner. Quiet atmosphere. Great breakfast with a huge variety of different things. We definitely recommend for a stay."
Germany
Andreas Johann
The price is NZ$137
includes taxes & fees
19 Nov - 20 Nov
To Spiti tis Sofias

2. Limneon Resort & Spa

Limneon Resort & Spa
5.0 star property
Kastoria
9.2 out of 10, Wonderful, (211 reviews)
"Wonderful stay. "
Canada
Konstantinos
The price is NZ$197
includes taxes & fees
8 Nov - 9 Nov
Limneon Resort & Spa

3. Calma Hotel & Spa

Calma Hotel & Spa
4.0 star property
Kastoria
9.6 out of 10, Exceptional, (39 reviews)
"Pleasant stay. Good amenities. Great staff. "
New Zealand
Robert
The price is NZ$150
includes taxes & fees
8 Nov - 9 Nov
Calma Hotel & Spa

4. Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel
4.0 star property
Kastoria
9.0 out of 10, Wonderful, (86 reviews)
"The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. "
United States
Michal
The price is NZ$222
includes taxes & fees
8 Nov - 9 Nov
Esperos Palace Luxury & Spa Hotel

5. Hotel Anastassiou

Hotel Anastassiou
2.0 star property
Kastoria
8.0 out of 10, Very good, (76 reviews)
"Nice simple stay."
United States
Jeffrey
The price is NZ$89
includes taxes & fees
17 Nov - 18 Nov
Hotel Anastassiou

6. Orologopoulos Mansion

Orologopoulos Mansion
5.0 star property
Kastoria
9.6 out of 10, Exceptional, (39 reviews)
"It is amazing!"
United States
Iren
The price is NZ$227
includes taxes & fees
8 Nov - 9 Nov
Orologopoulos Mansion

7. Guesthouse Vissinokipos

Guesthouse Vissinokipos
Kastoria
9.6 out of 10, Exceptional, (12 reviews)
"Wonderfull view and very friendly people.the place is avery dpecial artistic decorated.wonderfull weather.nice varieties for breakfast.price was ver good.i recommend it!"
United States
Carmen
The price is NZ$139
includes taxes & fees
6 Nov - 7 Nov
Guesthouse Vissinokipos

8. Kyknos De Luxe Hotel

Kyknos De Luxe Hotel
Kastoria
10.0 out of 10, Exceptional, (44 reviews)
"We had a lovely stay in kastoria, the hotel was great and breakfast was amazing. As a family of 4 the space in the room was ideal and the owners were extremely welcoming."
United Kingdom
Clare
The price is NZ$168
includes taxes & fees
8 Nov - 9 Nov
Kyknos De Luxe Hotel

9. Andromeda Boutique hotel

Andromeda Boutique hotel
4.0 star property
Kastoria
9.0 out of 10, Wonderful, (4 reviews)
"Πολυ καλο ξενοδοχείο σε καλη περιοχη"
Greece
JETMIR
The price is NZ$173
includes taxes & fees
8 Nov - 9 Nov
Andromeda Boutique hotel

10. Anesis Hotel

Anesis Hotel
2.0 star property
Kastoria
9.0 out of 10, Wonderful, (9 reviews)
"Fantastic hotel in the heart of Kastoria. The owners are lovely people, very helpful and made me feel right at home. Will definitely stay there again!"
Canada
Adam
The price is NZ$111
includes taxes & fees
11 Nov - 12 Nov
Anesis Hotel

11. Lūma Retreat

Lūma Retreat
Kastoria
The price is NZ$163
includes taxes & fees
11 Nov - 12 Nov
Lūma Retreat

12. Le Marron

Le Marron
4.0 star property
Voio
8.0 out of 10, Very good, (1 review)
The price is NZ$249
includes taxes & fees
16 Nov - 17 Nov
Le Marron

13. Guest House Ilektra

Guest House Ilektra
Voio
9.8 out of 10, Exceptional, (11 reviews)
"Wonderful views, easy to find, spacious rooms, and great hospitality."
United Kingdom
Maria
The price is NZ$107
includes taxes & fees
4 Dec - 5 Dec
Guest House Ilektra

14. Guesthouse Monopati

Guesthouse Monopati
Amyntaio
10.0 out of 10, Exceptional, (3 reviews)
The price is NZ$136
includes taxes & fees
14 Nov - 15 Nov
Guesthouse Monopati

15. Arhontiko Christodoulou

Arhontiko Christodoulou
2.0 star property
Prespes
The price is NZ$114
includes taxes & fees
7 Nov - 8 Nov
Arhontiko Christodoulou
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mesopotamia Hotel Reviews

Find out more about Mesopotamia

Top reasons to visit Mesopotamia

  • Outdoor Adventures: Mesopotamia offers a variety of outdoor activities, perfect for nature lovers and thrill-seekers alike.
  • Romantic Getaways: The picturesque setting makes it an ideal destination for couples looking for a romantic escape.
  • Rich Cultural Experiences: Explore fascinating museums and historical landmarks that showcase the region's heritage.
  • Scenic Lakes: Nearby lakes provide stunning views and opportunities for picnics and relaxation.
  • Warm Hospitality: Experience the friendly locals and welcoming atmosphere that enhance your stay.

Find great hotels near Mesopotamia

Discover a range of inviting hotels in Mesopotamia, Western Macedonia, perfect for every traveller's needs. Whether you're seeking a comfortable retreat after a day of adventure or a spa-themed getaway, the best accommodation options cater to both business and leisure visitors. Enjoy top-notch amenities and warm hospitality as you explore this charming region of Greece.

  • Esperos Palace Luxury & Spa Hotel: Nestled a mere 8.0km from Mesopotamia, the Esperos Palace Luxury & Spa Hotel is a sophisticated 4-star retreat. This property caters to those seeking a blend of business and relaxation. Its well-appointed facilities include a Conference Centre and multiple meeting rooms, ideal for corporate travellers. For those looking to unwind, the hotel boasts a full spa offering a range of treatments, including massages and indoor pool access. Enjoy a luxurious escape while still being close to your professional commitments.
  • Hotel Anastassiou: Situated 8.0km from Mesopotamia, Hotel Anastassiou is perfect for the adventurous traveller. This hotel combines business amenities, such as a Business Centre and meeting rooms, with exciting recreational opportunities. Guests can easily access ski lifts and shuttles, making it a fantastic choice for winter sports enthusiasts. Additionally, the surrounding area offers hiking, kayaking, and fishing for those who enjoy the great outdoors. Experience a vibrant blend of business and adventure at this welcoming hotel.
  • Kyknos De Luxe Hotel: Just 8.0km from Mesopotamia, the Kyknos De Luxe Hotel stands as a charming 3.5-star property that emphasises luxury and comfort. Ideal for business travellers, it features essential services and facilities that cater to professional needs. While the hotel provides an elegant atmosphere and attentive service, guests can expect a pleasant stay with easy access to the local attractions. Immerse yourself in a luxurious experience while enjoying the convenience of being close to the area's highlights.

Where to stay in Mesopotamia

Mesopotamia, a charming village in Western Macedonia, Greece, offers a delightful blend of outdoor adventures, romantic settings, and rich cultural experiences. Just a stone's throw away, discover the stunning landscapes and family-friendly atmosphere of Kastoria. Enjoy budget-friendly activities or indulge in luxury while exploring this picturesque region. With its friendly locals and unique charm, your trip to Mesopotamia promises to be an unforgettable journey filled with new discoveries.

  • Kastoria: Nestled in the heart of Western Macedonia, Kastoria is a captivating city renowned for its stunning lakeside views and rich history. The area is particularly popular among outdoor enthusiasts, offering activities such as skiing in nearby mountain ranges and relaxing at local spas. Visitors can explore the city's historic landmarks, including ancient monasteries and museums that showcase its cultural heritage. Peak travel times in September and during the winter months invite a lively atmosphere, making it an ideal destination for adventure-seekers and scenery lovers alike.
  • Árgos Orestikón: Located a mere 9.7km from Mesopotamia, Árgos Orestikón is a vibrant city that immerses visitors in its cultural allure. Known for its archaeological sites and museums, the town is a treasure trove for those interested in history and anthropology. The visitor experience is enriched by the beautiful places of worship that dot the landscape. With a steady flow of tourists peaking in September and the winter months, it's an excellent spot for cultural exploration and discovering the rich tapestry of local traditions.
  • Aposkepos: Aposkepos, a quaint village located 9.7km from Mesopotamia, offers a serene escape into nature. This charming destination sees a moderate influx of visitors, especially during the summer months from July to September. Its picturesque surroundings and tranquil atmosphere make it a perfect retreat for those looking to unwind. Aposkepos is ideal for leisurely walks and enjoying the natural beauty of the region, ensuring a peaceful and rejuvenating vacation experience.

Things to do in Mesopotamia

Mesopotamia offers a delightful blend of outdoor adventures and cultural experiences, making it perfect for a romantic getaway. Enjoy a scenic picnic in lush areas, embark on exciting city tours, or explore holiday parks. For those keen on adventure, river tours provide a unique perspective of the stunning landscape. Embrace the charm of this picturesque location as you immerse yourself in its natural beauty and rich heritage.

Shopping

In Mesopotamia, enjoy shopping at local boutiques and markets for unique gifts. If you're up for a drive, visit the nearby Katerini Shopping Centre, about 19.3km away, offering a mix of international brands and local stores for a delightful shopping experience.

Recreation

Experience serenity at the Thermal Springs of Pozar, where you can soak in natural hot springs surrounded by lush greenery. Enjoy rejuvenating spa treatments and explore nearby hiking trails that offer stunning views of the Macedonian landscape.

Adventure

In Mesopotamia, explore the enchanting trails of Mount Vourinos, perfect for hiking and birdwatching. Experience the thrill of kayaking on the serene Aliakmon River, or visit the picturesque Lake Kastoria for canoeing and cycling amidst stunning landscapes.

Nightlife

In Mesopotamia, the local tavernas come alive with traditional music and dancing, creating a vibrant atmosphere. The nearby cafes offer a relaxed vibe for late-night conversations, while bars serve local wines and spirits, making it an ideal spot for a lively evening out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mesopotamia

To save money on your trip to Mesopotamia, consider visiting in March or October to November when accommodation prices drop. Book your hotel about a month in advance or look for last-minute deals on Expedia. Saturdays generally offer the lowest rates, while Thursdays are pricier. Use Expedia’s search tool to filter by budget and sort from lowest to highest price. Combining hotel, flights, and activities into a package can also lead to significant savings, helping you enjoy your stay without breaking the bank.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Mesopotamia are March and October to November, where the prices are slightly lower. This is in comparison to April and July to August, where prices are slightly higher.
  • The best time to book a hotel: The cheapest time to book a hotel in Mesopotamia is usually 1 month out from when you are planning to stay, though if you're late to the party, have a look at Expedia's last minute deals - the green banner below the hotel's price indicates a discounted rate.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Mesopotamia is Saturday. The most expensive day to stay in Mesopotamia is Thursday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to refine your preferences, such as your budget, desired location, and the type of accommodation you prefer. To find the best value, make sure to sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save some cash by combining your Mesopotamia hotel booking with your flights and activities through an Expedia package.

Find the best attractions near Mesopotamia

Mesopotamia in Western Macedonia is perfect for outdoor and romantic getaways steeped in culture. Explore nearby lakes, fascinating history museums, and notable landmarks that cater to those seeking rich cultural experiences, stunning scenery, and relaxing beachtime. With plenty of attractions within and around Mesopotamia, you're sure to discover memorable activities and sights that will enhance your holiday adventure.

  • Kastoria Lake: Nestled a mere 8.0km from Mesopotamia, Kastoria Lake offers breathtaking scenery and a romantic atmosphere. Enjoy outdoor activities, stroll along the shore, or relax on the beach while soaking in the stunning views.
  • Folklore Museum of Kastoria: Located 8.0km away, this captivating history museum immerses you in the rich culture of the region. Explore traditional costumes, artefacts, and exhibits that showcase the local heritage and craftsmanship.
  • Taxiarhia of the Metropolis: This landmark, also 8.0km from Mesopotamia, blends trendy and luxury vibes with budget-friendly options. Discover its architectural beauty and enjoy a peaceful atmosphere, perfect for reflection and appreciation.

Best time to go to Mesopotamia

The best time to visit Mesopotamia can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Mesopotamia falls in August, when visitor numbers are moderately high and weather is sunny with no rain. The coolest average temperature in Mesopotamia falls in January, visitor numbers are moderately low and weather is mostly sunny with light rain.

Calendar MonthTemperaturePrecipitationCloudinessOccupancyPricing
January32.5°F (0.3°C)Light RainMostly SunnyModerately LowAverage
February36.1°F (2.3°C)Light RainMostly SunnyModerately LowAverage
March41.7°F (5.4°C)Light RainMostly SunnyAverageSlightly Low
April50.2°F (10.1°C)Light RainMostly SunnyAverageSlightly High
May57.9°F (14.4°C)Light RainMostly SunnyAverageAverage
June66.0°F (18.9°C)No RainMostly SunnyAverageAverage
July72.3°F (22.4°C)No RainSunnyModerately HighSlightly High
August72.5°F (22.5°C)No RainSunnyModerately HighSlightly High
September64.2°F (17.9°C)No RainMostly SunnyModerately HighAverage
October54.1°F (12.3°C)Light RainMostly SunnyAverageSlightly Low
November45.1°F (7.3°C)Light RainMostly SunnyModerately LowSlightly Low
December36.3°F (2.4°C)Light RainMostly SunnyAverageAverage

The nearest major airports for your trip to Mesopotamia

To visit Mesopotamia in Western Macedonia, Greece, you can fly into two major airports. Kozani Airport (KZI-Filippos) is situated 61.2km from Mesopotamia, with nearby hotels like Tselikas, a 3.5-star hotel just 1.6km away, and Anesis Hotel, located 3.2km away. Alternatively, Kastoria Airport (KSO-Aristoteles), 11.3km from Mesopotamia, offers luxurious options such as the 5-star Limneon Resort & Spa, 4.8km away, and Orologopoulos Mansion, 8.0km away. Various transportation services are available, including 24-hour airport shuttles and on-request transfers from these hotels, making access convenient for your stay in the area.

Frequently Asked Questions

What is the best area to stay in Mesopotamia?

The best area to stay in Mesopotamia is the main village centre, particularly near the central square, for access to local amenities and a convenient base for exploring.


The village centre is the heart of Mesopotamia, where you'll find the most activity. It's a compact area with a few local tavernas serving traditional Greek dishes and small shops for essentials. The central square is a natural gathering point, often bustling with locals in the evenings. Staying here puts you within easy reach of everything the village offers on foot.


For couples seeking a quiet and authentic Greek village experience, this area is ideal. You'll be able to enjoy leisurely meals at family-run tavernas and experience the relaxed pace of rural life. It's also a good starting point for exploring the surrounding natural beauty of Western Macedonia, like the nearby forests and hiking trails.


Visitors looking for a comfortable and convenient base to explore the wider region will also find the village centre suitable. While Mesopotamia itself is small, its central location within Western Macedonia makes it a practical spot for day trips to larger towns or natural attractions.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, although it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24 to 48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to ‘My Trips’ and selecting your reservation. To find flexible deals, filter your search by ‘Fully refundable property’ for hotels in Mesopotamia.

How can I save on a hotel booking in Mesopotamia with Expedia?

One Key™—Expedia’s free travel rewards programme—gives you instant access to discounts with Member Prices on Mesopotamia hotels. Plus, you’ll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

How much is the nightly rate for a hotel in Mesopotamia?

Prices for hotels in Mesopotamia often vary, but you can find a great deal from NZ$88 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by ‘Price: low to high’ for our cheapest rates.