Barrio de Santiago Travel Guide

Tourist Guide

Cathedral of San Ildefonso on the main square in Merida, Yucatan, Mexico. It is first cathedral finished on the American mainland and the only one built in 16th century
Cathedral of San Ildefonso on the main square in Merida, Yucatan, Mexico. It is first cathedral finished on the American mainland and the only one built in 16th century
Casa Frederick Catherwood which includes art and interior views
Casa Frederick Catherwood as well as an individual male
Casa Frederick Catherwood featuring a sunset

Our pick of the best Barrio de Santiago Hotel Deals

Casa Loreto 1893

Casa Loreto 1893

5 out of 5
619 Calle 59 Mérida
The price is NZ$447 per night from 28 Feb to 1 Mar
NZ$447
28 Feb - 1 Mar
includes taxes & fees
Stay at this luxury hotel in Mérida. Enjoy free Wi-Fi, free parking and room service. Popular attractions Paseo de Montejo and Plaza Altabrisa are located ...
9.8/10 Exceptional! (105 reviews)
Wonderful rooms and staff members were incredible!

Reviewed on 25 Feb 2026

Casa Loreto 1893
Hotel Unknown

Hotel Unknown

3.5 out of 5
559 Calle 53 Mérida YUC
Stay at this 3.5-star spa hotel in Mérida. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
9.2/10 Wonderful! (340 reviews)
The vibe is perfect! Super cute! Great staff!!

Reviewed on 26 Feb 2026

Get rates
Hotel Unknown
Hotel Ambassador Merida

Hotel Ambassador Merida

3 out of 5
Calle 59 No.546 X 68 Mérida YUC
The price is NZ$84 per night from 5 Mar to 6 Mar
NZ$84
5 Mar - 6 Mar
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular attractions ...
7.8/10 Good! (1,000 reviews)
the room was clean and the bed comfortable. The shower was very weak and it didn't always have hot water.

Reviewed on 4 Feb 2026

Hotel Ambassador Merida
Art 57 Hotel - Adults Only

Art 57 Hotel - Adults Only

3.5 out of 5
Calle 57, 543-A, entre 66 y 68 Mérida YUC
Stay at this boutique hotel in Mérida. Enjoy free breakfast, free Wi-Fi and a 24-hour front desk. Our guests praise the helpful staff in their reviews. Popular ...
8.4/10 Very Good! (777 reviews)
Good location. Clean rooms. Hot water showers. Breakfast was enough to get you going for the day. I would recommend it for the price we paid.

Reviewed on 26 Feb 2026

Get rates
Art 57 Hotel - Adults Only
Hotel Casa 57

Hotel Casa 57

3 out of 5
539 C. 57 Centro Mérida Yuc.
The price is NZ$117 per night from 1 Mar to 2 Mar
NZ$117
1 Mar - 2 Mar
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Our guests praise the helpful staff in their reviews. Popular ...
8.6/10 Excellent! (346 reviews)
Excellent service from front desk ladies very polite and friendly. Rooms expacious and clean bed was very comfortable. I definitely come back also very close fo main plaza

Reviewed on 17 Feb 2026

Hotel Casa 57
Hotel Embajadores

Hotel Embajadores

2.5 out of 5
Calle 61, 534 Mérida YUC
The price is NZ$87 per night from 1 Mar to 2 Mar
NZ$87
1 Mar - 2 Mar
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Popular attractions Paseo de Montejo and Plaza Altabrisa are located ...
7/10 Good! (414 reviews)
The room was clean, air conditioning 10 plus, bed was very comfortable, only issue was in the morning we had no hit water and toilet was running all night. Besides that very quite area, safe to walk from downtown.

Reviewed on 14 Feb 2026

Hotel Embajadores
See all 1,259 properties in Barrio de Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Holiday Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now

Other neighbourhoods around Barrio de Santiago

Merida Cathedral showing heritage architecture and night scenes

Mérida Centro

5/5(13 area reviews)

Mérida Centro is known for its abundant dining options, and you can plan a trip to Plaza Grande and US Visa Applicant Service Center while you're in town.

Mérida Centro
Modernized ancient meals were interesting and well worth a try. #troverfoodies

Santa Lucia

If you're looking for some top things to see and do in Santa Lucia and surrounding area, you can visit Plaza Grande and US Visa Applicant Service Center.

Santa Lucia
Default Image

San Juan

Though San Juan may not have many top sights, you can venture to the surrounding area to see attractions like US Visa Applicant Service Center and Plaza Grande.

San Juan
You must visit the Museum Palacio Canton while visiting Merida #lifeatexpediagroup #tlotravel #porqueviajares #becausetravellingis

Zona Paseo Montejo

While visiting Zona Paseo Montejo, you might make a stop by sights like Paseo 60 and Paseo de Montejo.

Zona Paseo Montejo
English Chocolates

García Ginerés

When in García Ginerés, you can plan a visit to Paseo 60 and Casa Montes Molina Museum, some noteworthy sights in the nearby area.

García Ginerés
Aerial camera at night showing the front of the Cathedral of Merida, Yucatan, Mexico.

Itzimná

Itzimná might not have many top sights, but Paseo 60 and Monument to the Fatherland are two attractions nearby that you can check out.

Itzimná

Barrio de Santiago Travel Guide

Choose two or more items and save on your trip: