Photo by Rick Tuers

Guadalupe District Hotels, Santa Fe

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Check prices for these dates

Tonight
12 Dec - 13 Dec
Tomorrow
13 Dec - 14 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Guadalupe District hotels

Porch
Guadalupe Inn

Guadalupe Inn

Guadalupe Inn
2.0 star property
Guadalupe District
9.2 out of 10, Wonderful, (1001)
"Cozy, quiet, and great for couples!"
United States
Emerson
The price is NZ$213
includes taxes & fees
19 Dec - 20 Dec
Guadalupe Inn
Rooftop bar
Drury Plaza Hotel in Santa Fe

Drury Plaza Hotel in Santa Fe

Drury Plaza Hotel in Santa Fe
3.5 star property
Downtown Santa Fe, 1.4 km from Guadalupe District
9.6 out of 10, Exceptional, (1420)
"The room, cleanliness, breakfast, hospitality, the location and front desk staff - everything was fantastic!"
United States
Manju
The price is NZ$269
includes taxes & fees
11 Jan - 12 Jan 2026
Drury Plaza Hotel in Santa Fe
Exterior
El Sendero Inn, an Ascend Collection Hotel

El Sendero Inn, an Ascend Collection Hotel

El Sendero Inn, an Ascend Collection Hotel
2.5 star property
Downtown Santa Fe, 1.2 km from Guadalupe District
9.0 out of 10, Wonderful, (1518)
"Clean, friendly staff, close to restaurants and shopping "
United States
Lydia
The price is NZ$179
includes taxes & fees
4 Jan - 5 Jan 2026
El Sendero Inn, an Ascend Collection Hotel
Terrace/patio
The Sage Hotel

The Sage Hotel

The Sage Hotel
3.0 star property
Don Diego, 0.6 km from Guadalupe District
8.0 out of 10, Very good, (2118)
"Clean room, friendly staff, great restaurant / bar and all at an incredible price!"
United States
Michael
The price is NZ$142
includes taxes & fees
15 Dec - 16 Dec
The Sage Hotel
Standard Room, 2 Queen Beds (Double Queen Room)
Coyote South

Coyote South

Coyote South
3.5 star property
Southside, 6.3 km from Guadalupe District
8.4 out of 10, Very good, (2974)
"Great stay, clean and affordable"
United States
Carlos
The price is NZ$131
includes taxes & fees
17 Dec - 18 Dec
Coyote South
Seasonal outdoor pool
Hilton Santa Fe Historic Plaza

Hilton Santa Fe Historic Plaza

Hilton Santa Fe Historic Plaza
4.0 star property
Downtown Santa Fe, 0.8 km from Guadalupe District
8.2 out of 10, Very good, (1006)
"Very nice staff, clean, very nicely appointed room"
United States
VIRGINIA
The price is NZ$226
includes taxes & fees
7 Jan - 8 Jan 2026
Hilton Santa Fe Historic Plaza
Outdoor pool, pool umbrellas, pool loungers
Hilton Vacation Club Villas de Santa Fe

Hilton Vacation Club Villas de Santa Fe

Hilton Vacation Club Villas de Santa Fe
3.0 star property
Northeast Santa Fe, 1 km from Guadalupe District
9.2 out of 10, Wonderful, (1008)
"It's a great place to stay! "
United States
Tonya
The price is NZ$167
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Vacation Club Villas de Santa Fe
Meeting facility
Inn at Santa Fe, SureStay Collection by Best Western

Inn at Santa Fe, SureStay Collection by Best Western

Inn at Santa Fe, SureStay Collection by Best Western
3.0 star property
Southside, 11 km from Guadalupe District
8.6 out of 10, Excellent, (2078)
"Room was spotless, staff helpful. "
United States
Sol
The price is NZ$141
includes taxes & fees
12 Jan - 13 Jan 2026
Inn at Santa Fe, SureStay Collection by Best Western
Exterior
La Quinta Inn by Wyndham Santa Fe

La Quinta Inn by Wyndham Santa Fe

La Quinta Inn by Wyndham Santa Fe
3.0 star property
Southside, 8.3 km from Guadalupe District
7.0 out of 10, Good, (1596)
"Convenient location "
United States
INDIRA
The price is NZ$119
includes taxes & fees
11 Jan - 12 Jan 2026
La Quinta Inn by Wyndham Santa Fe
Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas
Hotel Glorieta

Hotel Glorieta

Hotel Glorieta
3.5 star property
1.6 km from Guadalupe District
8.0 out of 10, Very good, (40)
"Loved the decor"
United States
Marian
The price is NZ$226
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Glorieta
Casita Bonita (Pet Friendly) | Private kitchen
Santa Fe Motel & Inn

Santa Fe Motel & Inn

Santa Fe Motel & Inn
2.5 star property
Railyard Arts District, 0.5 km from Guadalupe District
9.4 out of 10, Exceptional, (1000)
"Friendly and helpful staff, great location close to the Square, and nice rooms."
United States
Sonia
The price is NZ$216
includes taxes & fees
11 Jan - 12 Jan 2026
Santa Fe Motel & Inn
Terrace/patio
Hampton Inn Santa Fe South

Hampton Inn Santa Fe South

Hampton Inn Santa Fe South
2.5 star property
Southside, 6.5 km from Guadalupe District
8.8 out of 10, Excellent, (744)
"Clean, comfortable rooms, and friendly staff:)"
United States
Christin
The price is NZ$174
includes taxes & fees
10 Jan - 11 Jan 2026
Hampton Inn Santa Fe South
Free buffet breakfast
Holiday Inn Express & Suites Santa Fe by IHG

Holiday Inn Express & Suites Santa Fe by IHG

Holiday Inn Express & Suites Santa Fe by IHG
2.5 star property
Southside, 6.3 km from Guadalupe District
9.0 out of 10, Wonderful, (852)
"Room was clean, the night staff was very friendly and helpful. "
United States
Trudy
The price is NZ$202
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Santa Fe by IHG
Outdoor pool, a heated pool, pool loungers
Inn of the Governors

Inn of the Governors

Inn of the Governors
3.5 star property
Downtown Santa Fe, 0.9 km from Guadalupe District
9.6 out of 10, Exceptional, (1473)
"VERY NICE STAY"
United States
MARK
The price is NZ$292
includes taxes & fees
12 Jan - 13 Jan 2026
Inn of the Governors
Dining
Eldorado Hotel & Spa

Eldorado Hotel & Spa

Eldorado Hotel & Spa
4.0 star property
Downtown Santa Fe, 0.8 km from Guadalupe District
8.8 out of 10, Excellent, (1003)
"The room was fantastic and clean, the breakfast was amazing as well! Very clean and very welcoming staff!"
United States
Phillip
The price is NZ$318
includes taxes & fees
6 Jan - 7 Jan 2026
Eldorado Hotel & Spa
Suite, 1 King Bed | View from room
Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder
4.0 star property
19.9 km from Guadalupe District
8.6 out of 10, Excellent, (1006)
"I love staying here, the golf and Casino, restaurants, spa are all amazing!"
United States
JESSICA
The price is NZ$212
includes taxes & fees
18 Dec - 19 Dec
Hilton Santa Fe Buffalo Thunder
Front of property
Inn and Spa at Loretto

Inn and Spa at Loretto

Inn and Spa at Loretto
4.0 star property
Downtown Santa Fe, 1.1 km from Guadalupe District
9.0 out of 10, Wonderful, (1001)
"Wonderful stay! Beautiful hotel with friendly helpful staff!"
United States
Kristi
The price is NZ$357
includes taxes & fees
6 Jan - 7 Jan 2026
Inn and Spa at Loretto
Hypo-allergenic bedding, down duvets, desk, laptop workspace
Hyatt Place Santa Fe

Hyatt Place Santa Fe

Hyatt Place Santa Fe
3.0 star property
Southside, 8.5 km from Guadalupe District
8.8 out of 10, Excellent, (1001)
"Awesome stay and the staff were great! My only comment for improvement is that there should be had soap in the rooms and in the restroom downstairs (room only had face bar soap). "
United States
Melanie
The price is NZ$209
includes taxes & fees
2 Jan - 3 Jan 2026
Hyatt Place Santa Fe
Exterior
Hotel Santa Fe

Hotel Santa Fe

Hotel Santa Fe
4.0 star property
Railyard Arts District, 0.5 km from Guadalupe District
9.2 out of 10, Wonderful, (1080)
"Lovely stay"
United States
Richard
The price is NZ$274
includes taxes & fees
14 Dec - 15 Dec
Hotel Santa Fe
Lobby sitting area
Motel 6 Santa Fe, NM - Downtown

Motel 6 Santa Fe, NM - Downtown

Motel 6 Santa Fe, NM - Downtown
2.0 star property
Railyard Arts District, 0.5 km from Guadalupe District
7.8 out of 10, Good, (1001)
"Room was nice, easy check in."
United States
Alex
The price is NZ$125
includes taxes & fees
12 Jan - 13 Jan 2026
Motel 6 Santa Fe, NM - Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Guadalupe District

Find the best Guadalupe District areas for the activities you enjoy most.

Downtown Santa Fe

Visitors to Downtown Santa Fe rave about its fascinating museums, popular shops and acclaimed art galleries. You might also want to make some time to see Santuario De Nuestra Senora de Guadalupe or Lensic Performing Arts Center while you're exploring the neighbourhood.

Canyon Road showing art and interior views

Historic Eastside

While visiting Historic Eastside, you might make a stop by sights like Canyon Road and Edition ONE Gallery.

Southside

Southside is known for its popular shops, and with sights like Meow Wolf and International Museum of Collage, Assemblage & Construction, you won't get bored spending a day wandering around this part of Santa Fe.

Tesuque

Tesuque is noteworthy for its spas, and you can make a stop at top attractions like Shidoni Foundry and Glenn Green Galleries & Sculpture Garden.

Northeast Santa Fe

While Northeast Santa Fe isn't home to many top sights, New Mexico Museum of Art and Cathedral Basilica of Saint Francis of Assisi are some notable places to visit nearby.

Top Guadalupe District Hotel Reviews

The Sage Hotel

The Sage Hotel

10/10 Excellent
"Courteous staff, good breakfast!"
Carrie 1-night trip
Posted 1 day ago
The Sage Hotel

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Guadalupe District?
You'll be sure to have fun exploring Santa Fe's Guadalupe District neighbourhood. Make sure that you visit Santa Fe Railyard and Santuario De Nuestra Senora de Guadalupe as part of your Guadalupe District travel plans.
What's a favourite place to stay in Guadalupe District?
Based on Expedia customer reviews, Guadalupe Inn is the highest ranked property in Guadalupe District. This hotel is a short 14-minute walk from Santa Fe Plaza, and it offers free breakfast and free WiFi.
How many hotels are there in the Guadalupe District area?
If you're searching for places to stay in Santa Fe, Expedia has something to meet your needs with 57 Guadalupe District hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Guadalupe District, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get the best options available in Guadalupe District.
What can I see and do in this Santa Fe neighbourhood?
Sights like El Museo Cultural, Art Vault and TAI Modern can be part of your cultural tour of Guadalupe District. As you're discovering the neighbourhood, Santa Fe Railyard and Santuario De Nuestra Senora de Guadalupe are some other places worth a visit. Santa Fe Farmers Market, SITE Santa Fe and Harrell House of Natural Oddities and Bug Museum are just a few of the places to visit in and around Guadalupe District. While you're out sightseeing, Andrea Fisher Fine Pottery and Lensic Performing Arts Center are a couple of additional sights to visit in Santa Fe.
How can I get around Guadalupe District and the greater Santa Fe area?
If you want to head out of town, you can hop aboard a train at Santa Fe Depot.