Fort Defiance State Park Tours and Activities

Stay near popular Fort Defiance State Park attractions

Fort Defiance State Park

7.4/10 (15 reviews)
You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.
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Top Fort Defiance State Park Hotel & Accommodation Deals

Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 out of 5
13201 Kessler Road Cairo IL
Quality Inn Cairo I-57
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St Charleston MO
Super 8 by Wyndham Charleston/Sikeston East MO
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Miller City IL
Peaceful secluded cabin located near Horseshoe Lake
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

2.5 out of 5
102 Drake St Charleston MO
The Riverstone Hotel Charleston-Sikeston
Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Villa Ridge IL
Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Kevil KY
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

Olive Branch IL
Cozy cabins on beautiful Horseshoe Lake
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Days Inn and Suites by Wyndham Sikeston
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.