Photo by Toshiaki Yoshitake

Spa Hotels & Resorts in São Tomé from NZ$253

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Check availability on São Tomé Spa Hotels

Tonight
31 Dec - 1 Jan
Tomorrow
1 Jan - 2 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Our top choices for São Tomé hotels with a spa

Poolside bar
Praia Accommodation

Praia Accommodation

Praia Accommodation
3.0 star property
São Tomé
7.4 out of 10, Good, (18)
"Great place to stay "
United States
Daniel
The price is NZ$253
includes taxes & fees
2 Jan - 3 Jan 2026
Praia Accommodation
Hair salon
SH Boutique Hotel

SH Boutique Hotel

SH Boutique Hotel
3.5 star property
São Tomé
8.6 out of 10, Excellent, (10)
"Staff were very accommodating "
United States
Simon Peter
SH Boutique Hotel
Outdoor pool, pool umbrellas, pool loungers
Hotel Praia

Hotel Praia

Hotel Praia
3.5 star property
São Tomé
7.4 out of 10, Good, (18)
"Solid, basic hotel. "
United States
Jonathan
The price is NZ$300
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Praia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top São Tomé Hotel Reviews

Pestana São Tomé

Pestana São Tomé

10/10 Excellent
"Wonderful stay, great staff, easy, relaxing delightful."
alexander 5-night trip
Posted 3 weeks ago
Pestana São Tomé

Frequently asked questions

Looking to holiday at a spa hotel in São Tomé?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Spa hotels are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in São Tomé?
Sweet Guest House is a highly recommended spa hotel with a rooftop terrace. Spend an afternoon at Wele Health and Wellbeing where you'll find deep-tissue massages and hot stone massages. Another popular spa hotel in São Tomé is SH Boutique Hotel.
How many spa hotels are there in São Tomé?
Among Expedia's 27 accommodation options in São Tomé, there are 2 spa hotels.
What's there to see and do in São Tomé?
Enjoy São Tomé with a stop at Estadio Nacional 12 de Julho, São Sebastião Museum and Palácio dos Congressos. If you have some spare time during your trip, you might want to check out Pico São Tomé and Coffee Museum.
What is a São Tomé spa hotel?
Spa hotels in São Tomé have on-site spas which offer services including therapies and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation and relaxation.