Default HTG hotel image

Book Distrito Santiago Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Top Cities in Distrito Santiago

A historic church with two towers and a large central dome, surrounded by parked cars and a street.
HotelsHotels

Santiago

Santiago
A lush valley with dense green forests, rolling hills, and a cloudy sky.
HotelsHotels

Nuevo Santiago

Nuevo Santiago

Check prices for these dates

This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Distrito Santiago hotels

A pool surrounded by palm trees and a tiled roof structure.

1. Hotel Gran David

Hotel Gran David
3.5 star property
Santiago
8.6 out of 10, Excellent, (443 reviews)
"Great place to stay. I would stay there again."
United States
Roxani
The price is NZ$173
includes taxes & fees
22 Oct - 23 Oct
Hotel Gran David
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.

2. HOTEL VISTA LAGO

HOTEL VISTA LAGO
3.0 star property
La Pena
9.4 out of 10, Exceptional, (126 reviews)
"We had a very nice room with lake view, private terrace with hammock. Breakfast was very good too, pool and garden very nice and clean. Would always go back."
United States
Hedwig
The price is NZ$137
includes taxes & fees
17 Oct - 18 Oct
HOTEL VISTA LAGO
A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.

3. Hotel Mykonos Panama

Hotel Mykonos Panama
3.5 star property
Nuevo Santiago
8.8 out of 10, Excellent, (600 reviews)
"Very well located"
United States
Ismael
The price is NZ$165
includes taxes & fees
22 Oct - 23 Oct
Hotel Mykonos Panama
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.

4. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
3.0 star property
Nuevo Santiago
9.0 out of 10, Wonderful, (14 reviews)
"The front desk gentleman was very helpful and took extra measures to see that I was taken care of. A great asset to your hotel."
United States
James
The price is NZ$102
includes taxes & fees
22 Oct - 23 Oct
Hotel Plaza Los Tucanes
A hotel courtyard at night with a central pathway, palm trees, and well-lit buildings.

5. Hotel La Hacienda

Hotel La Hacienda
3.0 star property
Rodrigo Luque
8.6 out of 10, Excellent, (4 reviews)
"Nos gustó mucho la decoración, la comida excelente, encontrar un espacio temático mexicano fuera de este país es muy especial"
Panama
Anonymous traveller
Hotel La Hacienda
A swimming pool with a tiled deck, a covered seating area, and a multi-story building with balconies in the background.

6. Hotel Plaza

Hotel Plaza
3.0 star property
Nuevo Santiago
7.6 out of 10, Good, (35 reviews)
"It's a 35 $ a night hotel !!"
United States
Olivier
Hotel Plaza
A cozy room with a bed, a small table, and a chair.

7. Perfect 1-bedroom bungalow with AC in peaceful Playa reina

Perfect 1-bedroom bungalow with AC in peaceful Playa reina
Santiago
The price is NZ$214
includes taxes & fees
16 Oct - 17 Oct
Perfect 1-bedroom bungalow with AC in peaceful Playa reina
A spacious living area with a marble floor, a staircase, a kitchen with a black countertop, and a seating area with a black sofa.

8. HOTEL CORPORATIVO PLAZA COROTÚ

HOTEL CORPORATIVO PLAZA COROTÚ
3.0 star property
Santiago
HOTEL CORPORATIVO PLAZA COROTÚ
A modern kitchen with dark cabinetry, a large refrigerator, and a dining area with a dark table and chairs.

9. Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.

Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.
Panama
Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Distrito Santiago Hotel Reviews

Bambuda Santa Catalina

Bambuda Santa Catalina

10/10 Excellent
"We had such a wonderful stay at this beautiful hotel. The location, atmosphere, and people made it a truly special experience, even though our trip ended with a devastating earthquake. My heart breaks for the owners, staff, and entire Santa Catalina community who have been impacted by this disaster. This is such a special place, filled with wonderful people, and I know this hotel will come back from this. I hope travelers will continue to support this hotel and this beautiful community as they rebuild. We will absolutely be back. ❤️"
Caitlin 4-night trip
Posted 3 days ago
Bambuda Santa Catalina