A coastal landscape with a bridge, islands, and a marina.

Holiday Homes in Daufuskie Island

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
6 Nov - 8 Nov
In two months
18 Dec - 20 Dec
In three months
15 Jan - 17 Jan
In four months
12 Feb - 14 Feb

Our top choices for Daufuskie Island holiday homes

A modern kitchen with white cabinetry, stainless steel appliances, and a central island with bar stools.

1. Ocean Dreamer! New custom home nestled in the peaceful Historic District!

Ocean Dreamer! New custom home nestled in the peaceful Historic District!
Historic District
10.0 out of 10, Exceptional, (16 reviews)
"Beautiful house ! On gorgeous Daufuskie Island ."
United States
Teisha L.
The price is NZ$922
includes taxes & fees
25 Oct - 26 Oct
Ocean Dreamer! New custom home nestled in the peaceful Historic District!
A spacious living room with a sofa, armchair, and a coffee table. There is a TV and a lamp on a side table.

2. Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown

Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown
Sea Pines
10.0 out of 10, Exceptional, (113 reviews)
"Stay was wonderful! Will be back to visit again!"
United States
Brittany W.
The price is NZ$586
includes taxes & fees
2 Nov - 3 Nov
Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown
A modern living room with a sofa, a coffee table, and a fireplace. There is a kitchen area with a sink and cabinets.

3. New Meets Nostalgic- Cottage Sleeps 8

New Meets Nostalgic- Cottage Sleeps 8
3.5 star property
Whitemarsh Island
10.0 out of 10, Exceptional, (2 reviews)
"The best stay, beds were so comfortable and the location was perfect! So clean and smelled so good. Can’t wait to come back!"
United States
Emily
The price is NZ$475
includes taxes & fees
25 Oct - 26 Oct
New Meets Nostalgic- Cottage Sleeps 8
A balcony with two wooden chairs and a small table, overlooking a beach.

4. Desoto Beach Terraces

Desoto Beach Terraces
3.0 star property
South Beach
8.4 out of 10, Very good, (125 reviews)
"The property is unique but has the best views. The inside is dated and they do not provide housekeeping during your stay- was not aware of that."
United States
Karolyn Hanson
The price is NZ$364
includes taxes & fees
1 Nov - 2 Nov
Desoto Beach Terraces
A modern kitchen with black cabinets, stainless steel appliances, a marble countertop, and a pendant light.

5. Modern Home Near Beach & City Dog Friendly

Modern Home Near Beach & City Dog Friendly
3.0 star property
Wilmington Island
The price is NZ$562
includes taxes & fees
4 Nov - 5 Nov
Modern Home Near Beach & City Dog Friendly
A modern kitchen with white cabinetry, stainless steel appliances, and a central island.

6. Nature Lovers Love 2033 Deer Island Treehouse Walkable to Harbour Town

Nature Lovers Love 2033 Deer Island Treehouse Walkable to Harbour Town
Sea Pines
9.2 out of 10, Wonderful, (40 reviews)
"Loved the location, the condo had everything we needed, and the host was great to work with."
United States
Scott R.
The price is NZ$801
includes taxes & fees
25 Oct - 26 Oct
Nature Lovers Love 2033 Deer Island Treehouse Walkable to Harbour Town
A courtyard with a central water feature, surrounded by brick flooring and benches.

7. Awesome Ocean View! Coligny Area! Updated and CLEAN 1 Bedroom! #380

Awesome Ocean View! Coligny Area! Updated and CLEAN 1 Bedroom! #380
South End
9.6 out of 10, Exceptional, (107 reviews)
"Awesome spot to stay with everything we needed. Really enjoyed the pool access, walking distance to the beach, and bikes included with the property."
United States
Will K.
The price is NZ$522
includes taxes & fees
31 Oct - 1 Nov
Awesome Ocean View! Coligny Area! Updated and CLEAN 1 Bedroom! #380
A deck with chairs overlooking a body of water, trees, and a sunrise.

8. The Robin House, Newly Furnished Lake Retreat Near Tybee Island & Savannah

The Robin House, Newly Furnished Lake Retreat Near Tybee Island & Savannah
Wilmington Island
9.8 out of 10, Exceptional, (45 reviews)
"The property was very clean and beautiful. The owners was quick to respond and made the check in and check out process very easy."
United States
Anthony C.
The price is NZ$698
includes taxes & fees
27 Oct - 28 Oct
The Robin House, Newly Furnished Lake Retreat Near Tybee Island & Savannah
A staircase with white railings and wooden steps leading to a landing.

9. The Bluffton Farmhouse

The Bluffton Farmhouse
Bluffton
10.0 out of 10, Exceptional, (126 reviews)
"Amazing place and host will for sure stay again"
United States
Jeffery A.
The price is NZ$788
includes taxes & fees
3 Nov - 4 Nov
The Bluffton Farmhouse
A compact kitchen with dark cabinets, a white countertop, and a central island with stools.

10. Best of both worlds - located between Savannah Downtown and Tybee Island.

Best of both worlds - located between Savannah Downtown and Tybee Island.
Whitemarsh Island
10.0 out of 10, Exceptional, (61 reviews)
"Our stay was short and sweet! Very nice!"
United States
Becky H.
The price is NZ$537
includes taxes & fees
26 Oct - 27 Oct
Best of both worlds - located between Savannah Downtown and Tybee Island.
A modern kitchen with white cabinets, a dining table with placemats, and a unique chandelier.

11. Old Town + Modern + Fire Pit + EV Charger

Old Town + Modern + Fire Pit + EV Charger
Old Town Bluffton
9.4 out of 10, Exceptional, (32 reviews)
"We have a lovely stay over the 4th of July. Perfectly located! The house was clean and well appointed. Check in was smooth and the hosts were very accessible."
United States
Mariah M.
The price is NZ$839
includes taxes & fees
26 Oct - 27 Oct
Old Town + Modern + Fire Pit + EV Charger
A waterfront hotel with multiple red-roofed buildings, a dock, and a marina.

12. Disney's Hilton Head Island Resort

Disney's Hilton Head Island Resort
3.5 star property
Mid Island
9.6 out of 10, Exceptional, (131 reviews)
"The room and property were incredible! Already booking my next stay"
United States
Melissa
Disney's Hilton Head Island Resort
A modern living room with a wooden ceiling, a TV, a sofa, a coffee table, and a dining area with bar stools.

13. Luxe Condo in Old Town Bluffton + Elevator + Walkable to everything!

Luxe Condo in Old Town Bluffton + Elevator + Walkable to everything!
Old Town Bluffton
9.8 out of 10, Exceptional, (99 reviews)
"Excellent location, very clean, will definitely repeat"
United States
Sean m.
The price is NZ$816
includes taxes & fees
9 Nov - 10 Nov
Luxe Condo in Old Town Bluffton + Elevator + Walkable to everything!
Lounge area in addition to plenty of dining space on deck.

14. SEA PINES, 3RD ROW BEACH HOUSE, GREAT LOCATION, NEWLY RENOVATED MAIN AREA

SEA PINES, 3RD ROW BEACH HOUSE, GREAT LOCATION, NEWLY RENOVATED MAIN AREA
Sea Pines
10.0 out of 10, Exceptional, (117 reviews)
"Beautiful property, fantastic location!"
United States
Lauren W.
The price is NZ$1,690
includes taxes & fees
1 Nov - 2 Nov
SEA PINES, 3RD ROW BEACH HOUSE, GREAT LOCATION, NEWLY RENOVATED MAIN AREA
A single-story house with a front porch, a blue door, and a number 14 on the front wall.

15. Tybee Island Sunrise

Tybee Island Sunrise
North Beach
Tybee Island Sunrise
A dining area with a wooden table and black chairs, large windows with curtains, and a geometric pendant light.

16. The Marshlight Retreat

The Marshlight Retreat
Wilmington Island
8.4 out of 10, Very good, (7 reviews)
"This was a great house for 6 women for 6 nights. The beds were great and the 3 bathrooms were a big plus. The house was clean and the kitchen stocked with everything we needed. Would stay again."
United States
Susan H.
The price is NZ$867
includes taxes & fees
1 Nov - 2 Nov
The Marshlight Retreat
A modern living room with a fireplace, a ceiling fan, and a large window with curtains.

17. GOLF CART! Remodeled home near Old Town, Xbox!

GOLF CART! Remodeled home near Old Town, Xbox!
Bluffton
10.0 out of 10, Exceptional, (42 reviews)
"House is beautiful, clean and very comfortable. Location is great - close to restaurants and stores. Really enjoyed our stay and will recommend it to family and friends."
United States
Steven F.
The price is NZ$815
includes taxes & fees
1 Nov - 2 Nov
GOLF CART! Remodeled home near Old Town, Xbox!
A living room with a sofa, armchairs, a coffee table, a fireplace, a television, and a ceiling fan.

18. Flo’s Hideaway in the Heart of Thunderbolt just outside Savannah city limits

Flo’s Hideaway in the Heart of Thunderbolt just outside Savannah city limits
Thunderbolt
10.0 out of 10, Exceptional, (168 reviews)
"Great location and great communication from the host."
United States
Glen T.
The price is NZ$524
includes taxes & fees
25 Oct - 26 Oct
Flo’s Hideaway in the Heart of Thunderbolt just outside Savannah city limits
A modern kitchen with wooden cabinets, a central island, and a large window.

19. Beautiful Island Home

Beautiful Island Home
Talahi Island
9.8 out of 10, Exceptional, (38 reviews)
"Clean, comfortable beds, great location, easy check in, great communication. No complaints!"
United States
Arlene A.
Beautiful Island Home
A covered outdoor area with a wooden deck, a sofa with cushions, a table, and a ceiling fan.

20. Cute 2br/2ba Lighthouse View Cottage ~Walk to the beach

Cute 2br/2ba Lighthouse View Cottage ~Walk to the beach
North Beach
9.6 out of 10, Exceptional, (33 reviews)
"Thank you for this wonderful home! Great location."
United States
Kathy N.
Cute 2br/2ba Lighthouse View Cottage ~Walk to the beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Daufuskie Island Hotel Reviews

The DeSoto

The DeSoto

8/10 Good
"The room was clean except where it wasn't. The bathtub drain was a real eyesore with layers of putty around the drain that were peeling and even not dried. The bed skirt had something dried and crusted on it, and had not been changed. The lobby nice, balcony view awesome, pool area nice but seasonal service, staff helpful, no quick food to grab in lobby until the coffee shop is open (7am-3pm)"
Blythe 1-night trip
Posted 3 hours ago
The DeSoto

Find out more about Daufuskie Island

Daufuskie Island Holiday Homes information

Number of reviews
1,302
Accommodation
5749 Holiday Homes
Lowest Price
NZ$364
Highest Price
NZ$1,690