Search Commerce hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Commerce hotels

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (19)
Located just minutes from popular attractions like Show Me Centre and Isle Casino, this hotel offers free WiFi and parking. Relax in the garden after exploring Cape Girardeau's highlights, with convenient access to the municipal airport.

"My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! "
United States
Kim
The price is NZ$295
includes taxes & fees
1 Jan - 2 Jan 2026
Rockwood Inn

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.0 out of 10, (206)
This budget-friendly motel offers convenient free WiFi and parking near Cape Splash Family Aquatic Centre and Show Me Centre. With 24-hour front desk service, it provides a practical base for exploring Cape Girardeau attractions.

"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is NZ$111
includes taxes & fees
4 Jan - 5 Jan 2026
Town House Inn Cape Giradreau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1003)
Walking distance to restaurants and shops, this peaceful hotel offers complimentary breakfast, WiFi, and parking. Swim year-round in the indoor pool or unwind in the spa pool after exploring nearby attractions like Cape Splash Family Aquatic Centre.

"Awesome stay!"
United States
Breckin
The price is NZ$174
includes taxes & fees
30 Jan - 31 Jan 2026
Drury Inn & Suites Cape Girardeau

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (104)
Conveniently located near Shawnee National Forest, this Cape Girardeau hotel offers morning swims in the indoor pool and energising workouts at the fitness centre. Enjoy free breakfast before exploring nearby nature attractions.

"It was a nice stay"
United States
Douglas
The price is NZ$175
includes taxes & fees
7 Jan - 8 Jan 2026
Tru By Hilton Cape Girardeau

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very good, (886)
"Room was clean and spacious."
United States
George
The price is NZ$145
includes taxes & fees
25 Jan - 26 Jan 2026
Candlewood Suites Cape Girardeau by IHG

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (785)
Located near Shawnee National Forest and Mississippi River, this hotel offers complimentary breakfast, WiFi and parking. Unwind in the indoor pool, utilise the fitness centre or relax on the terrace. Clean rooms feature refrigerators and microwaves.

"Excellent stay"
United States
Christina
The price is NZ$205
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn Cape Girardeau I 55 East

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (145)
Enjoy free continental breakfast and complimentary parking at this modern Cape Girardeau retreat. The indoor pool offers year-round swimming, while Fort D Historic Site and Cape Splash Family Aquatic Centre are just minutes away.

"Clean room great breakfast "
United States
Carl
The price is NZ$171
includes taxes & fees
8 Jan - 9 Jan 2026
Fairfield Inn & Suites by Marriott Cape Girardeau

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
This peaceful hotel offers a quiet atmosphere just minutes from Shawnee National Forest and Cape Splash Family Aquatic Centre. Nearby restaurants and stores enhance convenience while helpful staff ensure a comfortable stay with free WiFi and daily housekeeping.

"Nice place for a stay at a reasonable price."
United States
Arthur
The price is NZ$136
includes taxes & fees
4 Jan - 5 Jan 2026
Pear Tree Inn Cape Girardeau Near the Medical Center

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
This centrally located hotel offers convenient access to restaurants and shopping. Take advantage of the indoor pool and fitness centre after exploring nearby Cape Splash Family Aquatic Centre. Free breakfast, WiFi, and parking enhance your stay with attentive staff ready to assist.

"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is NZ$177
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (479)
Located near Riverfront Park and Isle Casino, this business-friendly hotel offers exciting gaming, 2 restaurants including Beacon 53 for American cuisine, plus free WiFi and parking for convenient exploration of Cape Girardeau.

"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is NZ$181
includes taxes & fees
4 Jan - 5 Jan 2026
The Riverview

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (689)
Escape to this Cape Girardeau hotel with an outdoor pool, just minutes from Shawnee National Forest. Enjoy free breakfast, WiFi, and parking. The helpful staff ensures a pleasant stay while nature attractions and the Mississippi River await nearby.

"The room was clean and nice. The breakfast was really good."
United States
Kalani
The price is NZ$115
includes taxes & fees
8 Jan - 9 Jan 2026
Quality Inn Cape Girardeau North

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (469)
Wake up to Mississippi River views at this city centre hotel, steps from Riverfront Park and Shawnee National Forest. After exploring, return to The Bistro for American cuisine or unwind at the bar. The 24-hour fitness centre and in-room refrigerators enhance your stay.

"Very nice hotel within walking distance to many good restaurants "
United States
Vicky
The price is NZ$244
includes taxes & fees
8 Jan - 9 Jan 2026
Courtyard by Marriott Cape Girardeau Downtown

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1000)
Explore Shawnee National Forest from this Cape Girardeau hotel offering complimentary breakfast, WiFi, and parking. Enjoy the indoor pool and spa pool after a day out, or dine at The Southerner restaurant. Each room includes handy refrigerators and microwaves.

"This Drury is our preferred place to stay when visiting family in Cape Girardeau. The hotel Staff is always warm and small town friendly! The hotel is nice and the breakfast buffet is outstanding!! "
United States
Michael
The price is NZ$175
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Plaza Hotel Cape Girardeau Conference Center

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (679)
"Great place "
United States
GUY
The price is NZ$166
includes taxes & fees
15 Jan - 16 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1004)
Located just off the highway near Sikeston dining and shopping, this hotel offers both indoor and outdoor pools for year-round swimming. Guests praise the peaceful atmosphere, helpful staff, and complimentary breakfast, parking, and WiFi.

"This our favorite place to stop for a good night sleep. "
United States
Eileen
The price is NZ$177
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Inn & Suites Sikeston, MO

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very good, (740)
Modern comfort awaits at this Jackson hotel with an indoor pool and fitness centre. Explore nearby Shawnee National Forest or visit Cape Girardeau Conservation Nature Centre after enjoying the complimentary breakfast and WiFi.

"Room was clean and affordable for one night. The morning person could have been more attentive to me being there for breakfast. No greeting at all and sat on her phone. I was the only one down in the breakfast area. Be more aware of her surroundings while working alone. "
United States
Lori
The price is NZ$149
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Suites Jackson-Cape Girardeau

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (121)
This Sikeston motel offers a convenient base for exploring nearby Central Park and Sikeston Depot Museum. Enjoy thoughtful amenities like free WiFi and parking alongside 24-hour front desk service for assistance anytime.

"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is NZ$109
includes taxes & fees
1 Jan - 2 Jan 2026
Country Yard Inn and Suite

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1004)
Wake up to complimentary breakfast at this quiet retreat near Shawnee National Forest. Guests love the peaceful atmosphere, helpful staff, and convenient location close to Cape Splash Family Aquatic Centre. Free WiFi and parking enhance the overall value.

"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
United States
Colleen
The price is NZ$136
includes taxes & fees
4 Jan - 5 Jan 2026
Pear Tree Inn Cape Girardeau West

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (615)
This Charleston motel offers complimentary on-the-go breakfast and WiFi for a hassle-free stay. Guests appreciate the helpful staff and free parking. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.

"Staff was great! Room was nice. "
United States
Lana
The price is NZ$118
includes taxes & fees
30 Jan - 31 Jan 2026
Super 8 by Wyndham Charleston/Sikeston East MO

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (275)
Start your day with complimentary full breakfast before exploring nearby attractions. This hotel provides free WiFi and parking, making it an ideal base for visiting Fort Defiance State Park and Ballard Wildlife Management Area.

"The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6. I was not satisfied at all."
United States
ReShena
The price is NZ$136
includes taxes & fees
17 Jan - 18 Jan 2026
Quality Inn Cairo I-57
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Commerce Hotel Reviews

More cheap accommodation in Commerce

Frequently asked questions

What's the best place to stay in Commerce?
Drury Plaza Hotel Cape Girardeau Conference Center, located 12.6 mi (20.3 km) from the heart of Commerce, is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are The Riverview and La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau. See all available top hotels, or vacation rentals in Commerce.
What are some of the best holiday rentals that Commerce has to offer?
Little Blue Cottage on Spanish: This holiday home rental outside of Commerce comes with WiFi so that you can feel at home during your trip. See all vacation rentals in Commerce.
If I need to cancel my hotel reservation in Commerce, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Commerce.
How is it to stay in Commerce?
Travellers to Commerce will find plenty to explore and enjoy. There are 79 hotels and other accommodation options in the surrounding area. Find out more about Commerce.
What should I see while I'm in Commerce?
A favourite place to visit is Mississippi River. You'll also find Isle Casino Cape Girardeau and Show Me Center in the area. Take a look at what more there is to see and do in Expedia's Commerce guide.
What's the seasonal weather in Commerce?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Commerce is 1491 mm.