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Cape Girardeau Holiday Rentals

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Holiday Rentals in Cape Girardeau

Fridge, microwave, oven, stovetop
Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (114)
"The place was perfect for our stay and was close to the farmers market and downtown shops. Highly recommend for location!"
The price is NZ$400
includes taxes & fees
19 May - 20 May
Serenity South -- Gardens, River-Views, and Refreshing Space
Exterior
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
9.8 out of 10, Exceptional, (17)
"Town was cute and ecclectic, stay at VRBO gave the same vibes. Very clean and fun. We only stayed for 1 night but would love to come back- stopped by Annie Laurie’s, Indie House, Kenny’s Flippin Burgers, Ebb and Flow brewery and Broadway Bistro/vintage store. We recommend all of them!"
The price is NZ$242
includes taxes & fees
22 May - 23 May
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Aerial view
Loft Apartment Across From Semo University Houch Field House. Walk To Events
10.0 out of 10, Exceptional, (70)
"Just like home"
The price is NZ$297
includes taxes & fees
24 May - 25 May
Loft Apartment Across From Semo University Houch Field House. Walk To Events
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Exterior
4-acre Home with Multiple Decks: Pool Table | Putt-Putt I 4 miles to Downtown
9.2 out of 10, Wonderful, (20)
"This property was perfect for our family and our 4 boys really enjoyed the mini golf, pool table, couch swing and signing the wall. We will definitely be coming back on our travels. Unique decor and beautiful space! "
The price is NZ$630
includes taxes & fees
22 May - 23 May
4-acre Home with Multiple Decks: Pool Table | Putt-Putt I 4 miles to Downtown
Interior
Updated 3 bedroom unit with balcony!
10.0 out of 10, Exceptional, (1)
"Very nice place only downsize albeit cute is the claw foot tub with make shift shower, The unit worked very well for what we were looking for near SEMO campus"
Updated 3 bedroom unit with balcony!
Exterior
Quaint, Beautiful Home next to SEMO and Hospital
9.8 out of 10, Exceptional, (18)
"House was very nice and clean. Great neighborhood and super close to SEMO! Made visiting our son very nice having a place to stay other than a hotel room."
Quaint, Beautiful Home next to SEMO and Hospital
Property grounds
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
10.0 out of 10, Exceptional, (202)
"beautiful place. great location. recommend to anyone"
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Exterior
Charming Secluded Getaway Cabin within minutes of amenities
10.0 out of 10, Exceptional, (9)
"This place is amazing if what you want is relaxing. My wife and I stayed here for the total eclipse and did not see another person for our whole stay. This place sets the standard for secluded. The cabin had everything you could need for a great stay. Price was very reasonable. We could not be happier. "
Charming Secluded Getaway Cabin within minutes of amenities
Private kitchen
Little Blue Cottage on Spanish
8.8 out of 10, Excellent, (32)
"We stayed here to visit our two children going to SEMO. Everything about the place was perfect for a couple. The place was cute and the location was perfect"
The price is NZ$180
includes taxes & fees
19 May - 20 May
Little Blue Cottage on Spanish
Property grounds
The Twisted Sassafras Treehouse
10.0 out of 10, Exceptional, (7)
"The property was exactly as advertised. They’ve truly thought of so many little things that made our stay so enjoyable. There was a severe weather alert at 4 am during our stay and the hosts were checking on us the entire time to be sure all was well. We will definitely be back, for a longer stay next time! 🙂"
The price is NZ$564
includes taxes & fees
19 May - 20 May
The Twisted Sassafras Treehouse
Fridge, microwave, oven, stovetop
Charming 2-Story- C.1847 - River Views - Fast Wifi
9.6 out of 10, Exceptional, (10)
"Cape Girardeau is about the halfway point for us (Wisconsin) and friends from Mississippi. This VRBO is ideally located within walking distance to plenty of restaurants, shops and bars. Property is very clean, has the basics and communication with the owner was super easy. The saloon-style doors for the downstairs bathroom were a little unexpected, but we made it work. We enjoyed our stay and would recommended this property for a long weekend."
Charming 2-Story- C.1847 - River Views - Fast Wifi
Combined shower/bathtub, towels, soap, shampoo
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
10.0 out of 10, Exceptional, (1)
"Perfect property for family coming into town for football games! Great communication and fast responses!"
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
Exterior
Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau
10.0 out of 10, Exceptional, (3)
"Gorgeous home with unique finishings and a lot of attention to detail. A very quick trip did not allow for relaxing on the back screened in porch. "
Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau
Fridge, microwave, oven, stovetop
Steps to Southeast Hospital - Fast Wifi - King Bed
10.0 out of 10, Exceptional, (2)
"The house was perfect for our group. It was in a great location and was exactly as advertised. I would definitely stay here again!"
Steps to Southeast Hospital - Fast Wifi - King Bed
Fridge, microwave, oven, stovetop
Cozy Westend 4 queen beds, clean, quiet with a walk out basement
9.0 out of 10, Wonderful, (16)
"Very nice, well kept place. Host is very accommodating"
Cozy Westend 4 queen beds, clean, quiet with a walk out basement
Exterior
Luxury Loft Gallery next to Southeast Missouri State River Campus in Downtown CG
10.0 out of 10, Exceptional, (2)
"The property is beautifully designed for comfort and relaxation. The space beckons you to pause, rest, and enjoy your time away. They even remembered the small details to ensure your stay goes smoothly. Check in process was seamless and we had all the information we needed. I would highly recommend for your next visit to the area or weekend retreat!"
Luxury Loft Gallery next to Southeast Missouri State River Campus in Downtown CG
Interior
Large Home next to Southeast Hospital - 2 King Beds - Fast Wifi
10.0 out of 10, Exceptional, (4)
"This was a great place for us to stay while in town for a family emergency. We will be staying here again the next time we visit. Great communication, comfortable beds, clean and fully stocked with supplies."
Large Home next to Southeast Hospital - 2 King Beds - Fast Wifi
Property grounds
New cabin in the woods with private hot tub
10.0 out of 10, Exceptional, (71)
"Loved the location deep in the woods. Accommodations were perfectly clean and orderly. Hot tub was large and worked splendidly. Thanks"
New cabin in the woods with private hot tub
Exterior
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
10.0 out of 10, Exceptional, (336)
"Very please and enjoyed our stay. I highly recommend the place. I will make a suggestion for the cleaner. My wife has a skin sensitivity and we have come accustom to using only soaps that have no smell. The bed linens and bath towels were washed with a scented detergent and for us was a bit too much. Other than that a great experience. Thank you for making a great place to get away."
The price is NZ$320
includes taxes & fees
19 May - 20 May
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Property grounds
Feels like your in a Tree House!On the Wine 🍷Trail! Fire🔥Pit Private Location
9.8 out of 10, Exceptional, (193)
"I loved being away from the hustle and bustle of the city. The home is cozy but the water pressure for showers was almost non existent. It would be nice to have better internet for rainy days. But overall nice stay and beautiful home and outdoor space."
Feels like your in a Tree House!On the Wine 🍷Trail! Fire🔥Pit Private Location
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See all available properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other types of properties in Cape Girardeau you may be interested in

BBQ/picnic area
Auburn Place Hotel And Suites
2.5 star property
8.8 out of 10, Excellent, (1002)
"18 years ago, my wife and I stayed in the honeymoon suite and it was wonderful. This time, we had the opportunity to stay there with our son and it was wonderful. The staff was very friendly and immediately took care of getting us checked-in so that we could make in time for our niece’s graduation. I would recommend this hotel to anyone traveling to Cape Girardeau, MO. Blessings to you! Robert and Katherine M."
The price is NZ$125
includes taxes & fees
27 May - 28 May
Auburn Place Hotel And Suites
Lobby
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, (1001)
"We never heard another person. Staff was wonderful."
The price is NZ$118
includes taxes & fees
22 May - 23 May
Pear Tree Inn Cape Girardeau West
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 star property
9.6 out of 10, Exceptional, (1000)
"Very nice hotel."
The price is NZ$217
includes taxes & fees
22 May - 23 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

You always said you would go on a dream holiday someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannonball into the deep end. Go ahead, unplug and unwind in style. When you book one of our Cape Girardeau holiday rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your holiday just got upgraded.

As much as you love your vacation rental, it’s always good to get out and explore to soak up Cape Girardeau. Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in Cape Girardeau. Seeing all the best attractions is bound to make you fall in love with Cape Girardeau. Who knows, you may even be tempted to extend your stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. 

It’s your escape so why share it? You deserve your own slice of paradise. Booking your holiday rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in Cape Girardeau short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find holiday rentals in Cape Girardeau?

Yes, there are holiday rentals in Cape Girardeau close to Cape Splash Family Aquatic Center, or you can select a more secluded option if you're looking for a relaxing stay. Visitors like the top-notch restaurants and shops in Cape Girardeau. Make sure you allow time to enjoy the riverfront during your holiday.

What are some of the best holiday rentals that Cape Girardeau has to offer?

Serenity South -- Gardens, River-Views, and Refreshing Space: This highly rated holiday home rental in Cape Girardeau is located on a river, and has a fireplace, a balcony and air conditioning to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Some other homes for rent in Cape Girardeau include Little Blue Cottage on Spanish and Charming 2-Story- C.1847 - River Views - Fast Wifi.

How many holiday rentals will I find in Cape Girardeau?

Choose from 23 Expedia holiday rentals in Cape Girardeau for a memorable holiday.

What can I see and do in Cape Girardeau?

Family-friendly attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center, whereas Riverfront Bridge Park and Trail of Tears State Park are a couple of great spots to enjoy the outdoors. While here, Isle Casino Cape Girardeau and Show Me Center are other places worth a visit.

What are holiday rentals like in Cape Girardeau?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Cape Girardeau. Holiday rentals offer amenities such as laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, a holiday rental can provide a sense of security away from public hotel lifts and busy front desks while still allowing you the experience of travel. You'll also find more space in a holiday rental than in a hotel, which is another reason why a holiday rental is an attractive choice for a small group gathering.

Recent reviews of Cape Girardeau properties
Expedia verified reviews

Auburn Place Hotel And Suites

Auburn Place Hotel And Suites

5/5 Excellent
"18 years ago, my wife and I stayed in the honeymoon suite and it was wonderful. This time, we had the opportunity to stay there with our son and it was wonderful. The staff was very friendly and immediately took care of getting us checked-in so that we could make in time for our niece’s graduation. I would recommend this hotel to anyone traveling to Cape Girardeau, MO. Blessings to you! Robert and Katherine M."
A verified traveller stayed at Auburn Place Hotel And Suites
Posted 3 days ago
Auburn Place Hotel And Suites