Cape Girardeau County Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to NZ$2,400 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Our pick of the best Cape Girardeau County Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is NZ$195 per night from 4 Aug to 5 Aug
NZ$195
4 Aug - 5 Aug
includes taxes & fees
9.6/10 Exceptional! (1,005 reviews)
"The evening manager’s reception is awesome. There are several things available, which saved me having to eat out. This saves me money on dinners, especially since 3 small alcohol beverages are included too. Of course, the breakfast is pretty great too!"

Reviewed on 27 July 2026

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is NZ$203 per night from 17 Aug to 18 Aug
NZ$203
17 Aug - 18 Aug
includes taxes & fees
9.4/10 Exceptional! (634 reviews)
"The staff and room was awesome! Very clean"

Reviewed on 26 July 2026

The Riverview
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
The price is NZ$157 per night from 28 July to 29 July
NZ$157
28 July - 29 July
includes taxes & fees
9/10 Wonderful! (813 reviews)
"Breakfast is good."

Reviewed on 26 July 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
See all 278 properties in Cape Girardeau County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Cape Girardeau County holiday package cost?
Perhaps less than you imagined — from a tempting , actually! By bundling hotels, flights and car rentals into your own customized travel package, your trip to Cape Girardeau County is just a few clicks away.
How do I get a cheap travel package to Cape Girardeau County?
Creating your own Cape Girardeau County holiday package with Expedia is one of the easiest ways to save. We have access to more than 550 air carriers and 1 000 000 properties spread across the globe. With such an awesome range to select from, you'll have no trouble creating your ideal trip.
What are the top hotels in Cape Girardeau County?
For hotels in Cape Girardeau with cosy beds and friendly service, you can't go past Drury Plaza Hotel Cape Girardeau Conference Centre and Pear Tree Inn Cape Girardeau West. If you're swinging by Jackson as well, you can look forward to a relaxing night's sleep at Holiday Inn Express Hotel & Suites Cape Girardeau I-55  an IHG Hotel or Auburn Place Hotel And Suites.
How far in advance should I book my Cape Girardeau County holiday?
Reserving your spot early with Expedia means one less thing to worry about. Most carriers advertise tickets up to 12 months in advance. Generally, this is the cheapest time to book. If circumstances have left you booking late, discount tickets to Cape Girardeau County sometimes occur in the weeks leading up to departure.
What does an Expedia Cape Girardeau County travel package include?
Choose from a combination of rental cars, hotels and flights. Once you've made your booking, you can add activities and tours. Want to pick your fare class? That's also possible. The choice is all yours when it comes to planning your perfect Cape Girardeau County getaway.
What should I know before booking a Cape Girardeau County travel package?
You'll save plenty with an Expedia travel package. Combine your flights, rental cars and hotels and land exciting discounts. Hotels aren't your only option, though. We have oceanfront condos, city apartments and everything in between!
Can I choose my airline with a Cape Girardeau County Expedia holiday package?
Definitely. Expedia has more than 550 airline partners to choose from around the world. With so much choice, finding the right carrier to bring you to Cape Girardeau County will be a breeze.
If I'm not able to travel, can I cancel my Cape Girardeau County holiday package?
Yes, you can. We realise life happens, so we're here to help if you have to make changes to your Cape Girardeau County holiday package. You may be able to cancel or amend your itinerary for free if you've booked in the last 24 hours. Your airline, hotel or car rental company may charge you a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for more information. Also, check your itinerary for the finer details on change fees.

Stay near popular Cape Girardeau County attractions

A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.