The best area to stay in Bissau is the city centre, particularly around Avenida Amílcar Cabral and the adjacent areas.This central district is the heart of Bissau, offering a good mix of amenities and easy access to key points of interest. You'll find a concentration of hotels, restaurants, and shops here. The presidential palace and other government buildings are also located within this area, contributing to its well-maintained appearance.The city centre is particularly suitable for business travellers. Its central location means you're close to government offices, financial institutions, and major transport links, making it efficient for meetings and appointments.