A calm river with boats, lush greenery, and a clear blue sky.

Independent in Big Pine Key

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
30 Aug - 31 Aug
Tomorrow
31 Aug - 1 Sept
Next weekend
4 Sept - 6 Sept
In two weeks
11 Sept - 13 Sept
Save an average of 15% on thousands of hotels when you're signed in

Top Big Pine Key Hotel Reviews

Fairfield Inn & Suites by Marriott Marathon Florida Keys

Fairfield Inn & Suites by Marriott Marathon Florida Keys

10/10 Excellent
"Everything is good Service Atención Pool"
Ariel 2-night trip
Posted 3 hours ago
Fairfield Inn & Suites by Marriott Marathon Florida Keys
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

10/10 Excellent
"Beautiful resort"
Silvia 1-night trip
Posted 4 hours ago
Isla Bella Beach Resort & Spa
Parmer's Resort

Parmer's Resort

10/10 Excellent
"We arrived early and staff allowed us to check in. Huge unit with an upstairs and downstairs with giant balconys and great views. The decor was dated but very comfortable and well maintained. We loved it."
Bryant 3-night trip
Posted 4 hours ago
Parmer's Resort
Kingsail Resort

Kingsail Resort

10/10 Excellent
"My Family and I we love this resort. Every time we decide to go to Florida Keys we choose Kingsail Resort."
Yunior 1-night trip
Posted 11 hours ago
Kingsail Resort
Coconut Cay Resort & Marina

Coconut Cay Resort & Marina

10/10 Excellent
"Everything was great in my stay"
Carlos 1-night trip
Posted 1 day ago
Coconut Cay Resort & Marina
Floating Sea Cove Resort & Marina

Floating Sea Cove Resort & Marina

10/10 Excellent
"Super great place"
Brian 1-night trip
Posted 3 days ago
Floating Sea Cove Resort & Marina
Banana Bay Resort & Marina

Banana Bay Resort & Marina

8/10 Good
"solid hotel, nice rooms breakfast could be better"
michael 2-night trip
Posted 4 days ago
Banana Bay Resort & Marina
Yacht Haven Marina

Yacht Haven Marina

10/10 Excellent
"Very clean nice and peaceful"
Melissa 4-night trip
Posted 7 days ago
Yacht Haven Marina
Sunshine Key RV Resort & Marina

Sunshine Key RV Resort & Marina

8/10 Good
"Our camper had no direction on how to turn on hot water so we took cold showers the first day since we arrived late and the office was closed. A guide in the camper on how to do things other than the map of the park and all the rules would’ve been nice."
Stacy 4-night trip
Posted 12 days ago
Sunshine Key RV Resort & Marina

Explore a world of travel with Expedia