Antofagasta Region Holidays

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Top destinations in Antofagasta Region

San Pedro de Atacama as well as a small group of people
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San Pedro de Atacama

San Pedro de Atacama
Antofagasta
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Antofagasta

Antofagasta

Our pick of the best Antofagasta Region Hotel Deals

Diego de Almagro San Pedro de Atacama

Diego de Almagro San Pedro de Atacama

3 out of 5
Toconao 460 San Pedro de Atacama Antofagasta
Fully refundableReserve now, pay when you stay
The price is NZ$217 per night from 3 Jan to 4 Jan
NZ$217
3 Jan - 4 Jan
8.2/10 Very Good! (329 reviews)
Great location, good breakfast and great staff.

Reviewed on 23 Dec 2025

Diego de Almagro San Pedro de Atacama
Noi Casa Atacama

Noi Casa Atacama

4.5 out of 5
Tocopilla E-8 San Pedro de Atacama Antofagasta
The price is NZ$487 per night from 11 Jan to 12 Jan
NZ$487
11 Jan - 12 Jan
8.6/10 Excellent! (246 reviews)
We had a very good stay. They are very accommodating and efficient. Location is good, close enough to the main st but far enough from the noises. Only thing is there’s no AC which might be typical for the region. They give you a fan which solves the issue. Overall, it’s very good .

Reviewed on 28 Dec 2025

Noi Casa Atacama
Hotel Cumbres San Pedro de Atacama

Hotel Cumbres San Pedro de Atacama

4 out of 5
Avenida Las Chilcas S/N San Pedro de Atacama Antofagasta
The price is NZ$636 per night from 19 Jan to 20 Jan
NZ$636
19 Jan - 20 Jan
8.8/10 Excellent! (474 reviews)
so nice 😍

Reviewed on 24 Oct 2025

Hotel Cumbres San Pedro de Atacama
See all 298 properties in Antofagasta Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Antofagasta Region holiday package cost?
From as low as . Yes, you read that right. Our Antofagasta Region packages are the best way to stretch your budget. Combine your hotels, flights and car rentals and discover this lively destination.
How do I get a cheap travel package to Antofagasta Region?
Our Antofagasta Region holiday packages promise plenty of savings for the savvy traveller. For the best deals, simply bundle your hotel, flights and activities into an affordable package. But impressive bargains are only the start of your next unforgettable adventure. Book with Expedia and you'll have more than 550 airlines and 1 000 000 properties throughout the world to pick from. Whatever your budget, there's a package that's perfect for you.
What are the top hotels in Antofagasta Region?
Have a look at ibis Antofagasta and NH Antofagasta. They're the first choice for lots of travellers to Antofagasta. If San Pedro de Atacama is on your travel itinerary, Park Hotel Calama and Noi Casa Atacama are cosy options.
How far in advance should I book my Antofagasta Region holiday?
It can be tricky to know when is the ideal time to book your trip to Antofagasta Region. But typically the earlier you book, the better the prices. Sometimes, you can reserve your flights and hotels up to a year before your departure date. If you're considering a last-minute getaway, no need to stress! There are fabulous deals featured on Expedia every single day.
What does an Expedia Antofagasta Region travel package include?
From hotels and airfares to rental cars, Expedia can help you shape an Antofagasta Region package that's perfect for you. Holidaying for a week or two? Consider a rental car, hotel and flight bundle. If you're taking a short break, a flight and hotel deal could be more your style. Activities can also be added once you've made your booking. Our holiday packages make it simple to save and plan.
What should I know before booking an Antofagasta Region travel package?
Tailor deals to suit your budget with an Expedia package. Airfares, hotels, rental cars — we're a one-stop shop for all of them. You'll save precious dollars just for bundling your bookings. Whether you're embarking on a skiing adventure or drinking cocktails on a beach, your perfect getaway is just clicks away.
Can I choose my airline with an Antofagasta Region Expedia holiday package?
Expedia has access to more than 550 airline partners worldwide, so you sure can! Simply select your preferred carrier and put together the perfect Antofagasta Region trip.
If I'm not able to travel, can I cancel my Antofagasta Region holiday package?
Whether it's your flight or hotel, you can cancel and rebook it. Locked in your Antofagasta Region holiday package in the last 24 hours? You may be able to make changes at no cost. For bookings older than that, you may be charged a fee by your hotel, airline or car rental company. For further information, visit our Customer Service Portal. We'll help you every step of the way.

Discover the most popular places to visit in Antofagasta Region

Valle de la Luna which includes desert views

Valley of the Moon

Treat your eyes to the variety of colors in a deserted valley that looks like a scene from a science fiction movie.

Valley of the Moon

Cerro Paranal Observatory

Commune with nature and explore the great outdoors at Cerro Paranal Observatory during your travels in Antofagasta. Amble around the area's seaside or visit its shops.

Cerro Paranal Observatory

Chuquicamata Mine

Learn about the local history of Calama with a stop at Chuquicamata Mine. Amble around the area's parks or visit its casinos.

Chuquicamata Mine

What to do in Antofagasta Region

San Pedro de Atacama: Stargazing Experience with Transfer

San Pedro de Atacama: Stargazing Experience

NZ$69
per adult
San Pedro de Atacama: Stargazing Experience
San Pedro de Atacama: Etno-Stargazing Tour with Transfer

San Pedro de Atacama: Etno-Stargazing Tour with Transfer

NZ$73
per adult
San Pedro de Atacama: Etno-Stargazing Tour with Transfer
Puritama Hot Springs Experience with Transfer and Entrance

Puritama Hot Springs Experience with Transfer and Entrance

NZ$156
per adult
Puritama Hot Springs Experience with Transfer and Entrance
See all activities in Antofagasta Region
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.