Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Top St. Louis 5 Stars Hotels

See all 332 Hotels in St. Louis
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis
    5.0 out of 5.0
     
     
    4.7 out of 5 (407 reviews)
    Nice Room Close to ArchRooms are great. We had a really nice view from the 14th floor. Restaurant is pricey but food and service were excellent.
    16 Apr 2018
    Map

    Five Star Hotels & Resorts in St. Louis

    Enjoy a luxurious getaway when you indulge in a 5-star hotel stay in St. Louis.

    • Browse the recommendations of other travellers like you
    • Search for the best hotel or resort in the neighbourhood you prefer
    • Book with Expedia.co.nz to always get the best price

    5-star accommodation in St. Louis offer upscale, personal service. From a concierge to valet parking, the amenities at St. Louis 5-star hotels will keep you most comfortable. In fact, you won’t have to lift a finger during your entire stay. Enjoy facilities that include swimming pools, spas, and fine dining. When it’s time to retire for the evening, expect plush bedding, fine bed linens, and exquisitely designed guest rooms.

    Book your next stay at one of 7 best 5-star accommodation in St. Louis here on Expedia.co.nz today. Once you have narrowed down your options based on your personal preferences, booking is fast and easy. You can start earning points with Expedia+ today, so the time to book is now.

    Recently booked St. Louis hotels

    Hollywood Casino & Hotel St. Louis
    3.5 out of 5.0
    Last booking: 1 minute ago
    Best Western Plus Pontoon Beach
    3.0 out of 5.0
    Last booking: 6 minutes ago
    Best Western Troy Hotel
    2.5 out of 5.0
    Last booking: 17 minutes ago
    Motel 6 Florissant, MO
    1.5 out of 5.0
    Last booking: 17 minutes ago
    Missouri Athletic Club
    3.5 out of 5.0
    Last booking: 21 minutes ago
    Motel 6 Hazelwood
    2.0 out of 5.0
    Last booking: 21 minutes ago
    Motel 6 Maryland Heights, MO
    2.0 out of 5.0
    Last booking: 21 minutes ago
    DoubleTree by Hilton Collinsville - St. Louis
    3.0 out of 5.0
    Last booking: 23 minutes ago
    Holiday Inn Express St Louis - Central West End
    3.0 out of 5.0
    Last booking: 27 minutes ago